CD38/NADase increases during aging, and causes NAD decline and subsequent mitochondrial dysfunction. <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911708/</ref>
Pharmacokinetic profile of quercetin in study participants. Plasma concentrations after the oral administration of quercetin formulated in different treatments at a total dose of 500 mg. AO (free quercetin), AP (Quercetin Phytosome), AW (Quercetin LipoMicel). Values are means ± SD, n = 12 for each point. AW significantly different from AO treatment, P < 0.005 performed with ANOVA followed by post hoc t tests (Bonferroni Correction).
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