Nicotinamide Mononucleotide (NMN): Difference between revisions

In November 2022, the US [[Food and Drug Administration (FDA)]] issued a statement saying that NMN may not be sold as a supplement, citing its status as being under investigation as a drug. This development is a reversal of the FDA's previous decision to allow its sale as a new dietary supplement (NDI). The reason for the reversal is unknown, but in December 2021, Metro International Biotech, a startup pharmaceutical company that has developed the NMN formulation MIB-626, wrote to the FDA: "As a company that has instituted publicly available clinical trials on ß-NMN, we request that FDA take the preclusion provision … seriously to protect the rights of companies that have spent significant time and research to develop drug products from competition from dietary supplements". According to Insider, the FDA confirmed that it had considered Metro's request. <ref>https://www.nmn.com/news/fda-bans-labeling-nmn-as-a-supplement</ref>

NMN is naturally present in a variety of foods, albeit in relatively small quantities. Here is a list of some foods known to contain NMN, along with their respective NMN content. <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668137/</ref>