2,851
edits
Creatine: Difference between revisions
no edit summary
No edit summary |
|||
| Line 26: | Line 26: | ||
Creatine supplementation has been associated with various health benefits which may contribute to its potential role in promoting longevity. Here are some of the potential benefits: | Creatine supplementation has been associated with various health benefits which may contribute to its potential role in promoting longevity. Here are some of the potential benefits: | ||
=== Cognitive Function === | === Cognitive Function === | ||
Robust evidence highlights the significance of creatine on cognitive function, particularly observed in individuals with creatine deficient syndromes known to deplete brain creatine stores. Creatine deficiency syndrome is marked by mental and developmental disorders, including learning delays and seizures. Notably, these symptoms are, to some extent, reversed by creatine supplementation. Human studies have yielded mixed results. While some studies have discovered benefits on cognitive functioning, others found no such effects, as comprehensively reviewed by Roschel and colleagues in 2022{{#pmid:35267907}}. | |||
When it comes to memory, results have varied across age groups. In aging adults (68–85 years), creatine supplementation of 20 g/day for 7 days improved memory measures such as forward number recall, backward and forward spatial recall, and long-term memory. Further, vegetarians saw working memory improvements after creatine supplementation of 5 g/day for 6 weeks. A direct comparison between omnivores and vegetarians revealed better memory post creatine supplementation in vegetarians than meat-eaters. However, some studies did not observe any beneficial effects of creatine on memory measures in children, adults, and older adults. | |||
Moreover, sleep deprivation, which is known to impact brain bioenergetics, seems to be another area where creatine supplementation shows promise. Preliminary evidence suggests that combining creatine supplementation with sleep deprivation can enhance cognitive function, especially when coupled with mild to moderate exercise. For instance, after 24 hours of sleep deprivation, those supplemented with creatine saw less change in performance from baseline in random movement generation, choice reaction time, balance, and mood state. Additionally, another experiment from the same group indicated that creatine supplementation counteracted the loss of complex central executive function due to sleep deprivation. | |||
Overall, there is mounting evidence suggesting that creatine supplementation can enhance certain cognitive functions, especially when brain bioenergetics are under stress, such as during sleep deprivation. | |||
=== Cardiovascular Health === | === Cardiovascular Health === | ||