Geroprotection

Geroprotection is defined as the "protection from the adverse effects of aging". A geroprotector is "any therapeutic agent that provides geroprotection".

Geroprotection refers to strategies and interventions aimed at delaying, preventing, or reversing age-related decline in health and function. This field encompasses a broad range of approaches, from lifestyle modifications to pharmaceutical interventions. Geroprotection operates through various biological mechanisms. These may include reducing oxidative stress, enhancing DNA repair, improving metabolic efficiency, modulating immune function, and regulating gene expression related to aging. Understanding these mechanisms is crucial for developing effective geroprotectors.

Types of Geroprotectors

Geroprotectors can be classified into several categories based on their nature and mode of action. This includes:

• Nutraceuticals: Natural food components with health benefits, such as antioxidants found in fruits and vegetables.
• Pharmaceuticals: Drugs specifically designed to target aging-related pathways, like metformin.
• Hormones and supplements: Substances that mimic or enhance hormonal functions, like melatonin or DHEA.

Research and Development

The field of geroprotection is rapidly evolving, with ongoing research into new potential geroprotectors. Clinical trials and animal studies are essential for assessing the efficacy and safety of these agents.

See Also

• Wiktionary - geroprotection
• Wiktionary - geroprotector