C57BL/6 mice: Difference between revisions

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    [[File:Black 6 mouse eating.jpg|thumb|C57BL/6, female, 22 weeks old]]
    '''C57BL/6''', often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common [[wikipedia:Inbred_strain|inbred strain]] of [[wikipedia:Laboratory_mouse|laboratory mouse]].
    '''C57BL/6''', often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common [[wikipedia:Inbred_strain|inbred strain]] of [[wikipedia:Laboratory_mouse|laboratory mouse]].


    It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of [[wikipedia:Congenic|congenic]] strains, easy breeding, and robustness.<ref name="Slate">{{cite news|url=http://www.slate.com/articles/health_and_science/the_mouse_trap/2011/11/black_6_lab_mice_and_the_history_of_biomedical_research.html|publisher=Slate.com|title=The Trouble With Black-6: A tiny alcoholic takes over the lab.|author=Engber, Daniel|date=17 November 2011}}</ref>
    It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of [[wikipedia:Congenic|congenic]] strains, easy breeding, and robustness.<ref name="Slate">Engber, Daniel (17 November 2011). [http://www.slate.com/articles/health_and_science/the_mouse_trap/2011/11/black_6_lab_mice_and_the_history_of_biomedical_research.html "The Trouble With Black-6: A tiny alcoholic takes over the lab"]. Slate.com.</ref>


    The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 months.<ref>{{cite web|url=https://www.lifespan.io/topic/the-c57bl-6-black-6-mouse-strain/|title=The C57BL 6 (Black 6) Mouse Strain|website=[[Life Extension Advocacy Foundation|Lifespan.io]]|access-date=27 July 2023}}</ref>
    The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 months.<ref>{{cite web|url=https://www.lifespan.io/topic/the-c57bl-6-black-6-mouse-strain/|title=The C57BL 6 (Black 6) Mouse Strain|website=[[Life Extension Advocacy Foundation|Lifespan.io]]|access-date=27 July 2023}}</ref>


    == See also ==
    == See Also ==


    * [[Wikipedia:C57BL/6]]
    * [[Mice]]
    * [[Wikipedia:C57BL/6|Wikipedia article]]


    == References ==
    == References ==
    <references />
    <references />
    [[Category:Research]]
    [[Category:Model Organism]]

    Latest revision as of 01:33, 8 December 2023

    C57BL/6, female, 22 weeks old

    C57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse.

    It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of congenic strains, easy breeding, and robustness.[1]

    The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 months.[2]

    See Also

    References

    1. Engber, Daniel (17 November 2011). "The Trouble With Black-6: A tiny alcoholic takes over the lab". Slate.com.
    2. The C57BL 6 (Black 6) Mouse Strain, https://www.lifespan.io/topic/the-c57bl-6-black-6-mouse-strain/