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Nicotinamide Mononucleotide (NMN): Difference between revisions
Nicotinamide Mononucleotide (NMN) (view source)
Revision as of 01:59, 26 December 2023
, 26 December 2023→Combination Therapy for Enhanced NAD+ Levels
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=== Combination Therapy for Enhanced NAD+ Levels === | === Combination Therapy for Enhanced NAD+ Levels === | ||
A variety of nutritional supplements are available in the market, which contains the compositions of NMN coupled with natural products. Despite this, the synergistic effects and transformation processes of NMN in such combinations are not fully understood. | |||
* With Resveratrol: NAD+ levels increased approximately 1.6 times in the heart and 1.7 times in muscle tissue. | |||
* With Ginsenosides (Rh2 & Rg3): NAD+ levels in lung tissue improved by about 2.0 times. | In a recent study, oral administration of NMN (500 mg/kg) was combined with either resveratrol (50 mg/kg) or ginsenosides (Rh2 & Rg3) (50 mg/kg) in [[C57BL/6 mice]] to assess the efficacy of these drug combinations. The results showed that the combination could increase NAD+ levels in specific mouse tissues compared to NMN alone:{{pmid|35844164}} | ||
* '''With''' '''Resveratrol''': NAD+ levels increased approximately 1.6 times in the heart and 1.7 times in muscle tissue. | |||
* '''With''' '''Ginsenosides (Rh2 & Rg3)''': NAD+ levels in lung tissue improved by about 2.0 times. | |||
These findings suggest that combining NMN with specific natural products like resveratrol or ginsenosides may amplify the beneficial effects on NAD+ levels, offering new avenues for treating age-related diseases or conditions linked to decreased NAD+ levels in specific tissues. | These findings suggest that combining NMN with specific natural products like resveratrol or ginsenosides may amplify the beneficial effects on NAD+ levels, offering new avenues for treating age-related diseases or conditions linked to decreased NAD+ levels in specific tissues. | ||