Mitochondrial Dysfunction: Difference between revisions

'''Mitochondrial Dysfunction''' is recognized as a central hallmark of aging and contributes to the pathogenesis of a wide range of age-related diseases. Mitochondria are known as the "powerhouses of the cell," responsible for producing the majority of the cellular energy in the form of adenosine triphosphate (ATP) through a process called oxidative phosphorylation. Beyond energy production, mitochondria are also involved in a variety of other important processes, including calcium homeostasis, apoptotic cell death, and the generation of reactive oxygen species (ROS). As organisms age, mitochondrial function tends to decline, leading to reduced energy production, increased oxidative damage, and impaired cellular function.