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Deregulated Nutrient Sensing: Difference between revisions
→Therapeutic Interventions
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==Therapeutic Interventions== | ==Therapeutic Interventions== | ||
Modulating nutrient sensing pathways offers potential therapeutic avenues for extending healthspan and treating age-related diseases: | Modulating nutrient sensing pathways offers potential therapeutic avenues for extending healthspan and treating age-related diseases: | ||
*'''Dietary Interventions''': Calorie restriction and intermittent fasting have been shown to beneficially modulate nutrient sensing pathways, leading to improved health and longevity. | *'''Dietary Interventions''': Calorie restriction and intermittent fasting have been shown to beneficially modulate nutrient sensing pathways, leading to improved health and longevity.{{pmid|25815989}} | ||
*'''Pharmacological Agents''': Drugs targeting these pathways, such as metformin (AMPK activator), rapamycin (mTOR inhibitor), and sirtuin activators, are being explored for their potential to mimic the beneficial effects of dietary interventions and treat age-related metabolic disorders. | *'''Pharmacological Agents''': Drugs targeting these pathways, such as metformin (AMPK activator), rapamycin (mTOR inhibitor), and sirtuin activators, are being explored for their potential to mimic the beneficial effects of dietary interventions and treat age-related metabolic disorders. | ||
*'''Lifestyle Modifications''': Exercise and dietary adjustments can influence the activity of nutrient sensing pathways and are recommended for maintaining metabolic health and preventing age-related diseases. | *'''Lifestyle Modifications''': Exercise and dietary adjustments can influence the activity of nutrient sensing pathways and are recommended for maintaining metabolic health and preventing age-related diseases. | ||