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Neurological Disorders: Difference between revisions
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* '''[[Zinc]]:''' Zinc is an essential trace element that plays a significant role in the brain and central nervous system. It's crucial for neurotransmitter function and brain signaling. Zinc is also important for neurogenesis, the process of generating new neurons. Deficiency in zinc can lead to a variety of neurological symptoms, including altered cognition, mood disorders, and learning difficulties. In neurodegenerative diseases such as Alzheimer's, zinc has been noted for its potential role in modulating synaptic function and in the pathogenesis of the disease. However, the exact mechanisms and therapeutic potential of zinc supplementation in these contexts are still subjects of ongoing research. | * '''[[Zinc]]:''' Zinc is an essential trace element that plays a significant role in the brain and central nervous system. It's crucial for neurotransmitter function and brain signaling. Zinc is also important for neurogenesis, the process of generating new neurons. Deficiency in zinc can lead to a variety of neurological symptoms, including altered cognition, mood disorders, and learning difficulties. In neurodegenerative diseases such as Alzheimer's, zinc has been noted for its potential role in modulating synaptic function and in the pathogenesis of the disease. However, the exact mechanisms and therapeutic potential of zinc supplementation in these contexts are still subjects of ongoing research. | ||
=== Antioxidants === | === [[Antioxidant|Antioxidants]] === | ||
* '''[[Vitamin E]] and [[Selenium]]:''' These antioxidants play a crucial role in protecting the brain and nervous system against oxidative stress, which can damage cells and is implicated in conditions like stroke, Alzheimer's disease, and Parkinson's disease. Vitamin E, in particular, has been shown to support cognitive health and may slow the progression of Alzheimer's disease. | * '''[[Vitamin E]] and [[Selenium]]:''' These antioxidants play a crucial role in protecting the brain and nervous system against oxidative stress, which can damage cells and is implicated in conditions like stroke, Alzheimer's disease, and Parkinson's disease. Vitamin E, in particular, has been shown to support cognitive health and may slow the progression of Alzheimer's disease. | ||
* '''[[Coenzyme Q10]]:''' CoQ10 is involved in energy production within cells and acts as an antioxidant. It has been studied for its potential benefits in neurodegenerative disorders such as Parkinson's and Huntington's diseases, where mitochondrial dysfunction and oxidative stress are key features. | * '''[[Coenzyme Q10]]:''' CoQ10 is involved in energy production within cells and acts as an antioxidant. It has been studied for its potential benefits in neurodegenerative disorders such as Parkinson's and Huntington's diseases, where mitochondrial dysfunction and oxidative stress are key features. | ||
* '''[[Alpha-Lipoic Acid (ALA)]]:''' Alpha-Lipoic Acid is a naturally occurring compound that functions as an antioxidant in the body. It plays a crucial role in mitochondrial energy metabolism and is known for its ability to regenerate other antioxidants, such as Vitamin C and Vitamin E, enhancing their effectiveness. ALA has been particularly studied for its benefits in peripheral neuropathy, especially diabetic neuropathy. It helps improve nerve blood flow, reduce oxidative stress, and alleviate pain, burning, and numbness associated with neuropathy. Additionally, due to its antioxidant properties, ALA is being explored for potential benefits in other neurological conditions characterized by oxidative stress. | |||
=== Herbal Supplements === | === Herbal Supplements === | ||
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* '''[[Creatine]]:''' Often associated with muscle strength, creatine has also shown neuroprotective effects in various models of neurological diseases. It supports energy metabolism in brain cells and may offer benefits in conditions like Parkinson's disease, Huntington's disease, and ALS. | * '''[[Creatine]]:''' Often associated with muscle strength, creatine has also shown neuroprotective effects in various models of neurological diseases. It supports energy metabolism in brain cells and may offer benefits in conditions like Parkinson's disease, Huntington's disease, and ALS. | ||
* '''[[Acetyl-L-Carnitine]]:''' This supplement is involved in mitochondrial energy metabolism and has been explored for its benefits in peripheral neuropathy, especially related to diabetes, and in Alzheimer's disease. It helps transport fatty acids into mitochondria for energy production and has potential neuroprotective properties. | * '''[[Acetyl-L-Carnitine]]:''' This supplement is involved in mitochondrial energy metabolism and has been explored for its benefits in peripheral neuropathy, especially related to diabetes, and in Alzheimer's disease. It helps transport fatty acids into mitochondria for energy production and has potential neuroprotective properties. | ||
* '''[[NAD+ Precursor|NAD+ Precursors]]:''' [[Nicotinamide Adenine Dinucleotide (NAD+)]] is a vital coenzyme in cellular energy metabolism and plays a significant role in various cellular processes, including DNA repair, cell signaling, and aging. NAD+ levels naturally decline with age, and this reduction is linked to various age-related diseases, including neurodegenerative disorders. Supplementation with NAD+ precursors is thought to boost NAD+ levels in the body. This can potentially support cellular health, improve energy metabolism in brain cells, and offer neuroprotective effects. Studies are exploring their efficacy in conditions like Alzheimer's disease, Parkinson's disease, and other neurodegenerative and cognitive disorders. These precursors are a promising area of research for their potential to mitigate age-related decline in neurological function. | |||
=== Other Supplements === | === Other Supplements === | ||
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== Todo == | == Todo == | ||
* Include links to [[ | * Include links to [[Senescent Cells|senescent cells]] | ||
* {{pmid_text|35733475}} | * {{pmid_text|35733475}} | ||
* {{pmid text|36306110}} | * {{pmid text|36306110}} | ||
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<references /> | <references /> | ||
[[Category:Diseases]] | [[Category:Diseases]] | ||
[[Category:Age-Related Diseases]] | |||