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Biological Age: Difference between revisions
→Estimation Methods
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! Advantage | ! Advantage | ||
! Disadvantage | ! Disadvantage | ||
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| MLR | | MLR | ||
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* The standards of aging biomarkers lead to the paradox of CA | * The standards of aging biomarkers lead to the paradox of CA | ||
* MLR also distorts the BA at the regression edge and ignores discontinuity in the aging rate{{pmid|6873212}}{{pmid|3226152}}{{pmid|950448}} | * MLR also distorts the BA at the regression edge and ignores discontinuity in the aging rate{{pmid|6873212}}{{pmid|3226152}}{{pmid|950448}} | ||
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| PCA | | PCA | ||
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* PCA cannot avoid the paradox of CA and some statistical deficiencies of MLR{{pmid|16318865}} | * PCA cannot avoid the paradox of CA and some statistical deficiencies of MLR{{pmid|16318865}} | ||
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| Hochschild’s method | | Hochschild’s method | ||
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* Hochschild’s method is not based on the definition of BA | * Hochschild’s method is not based on the definition of BA | ||
* A large number of subjects are required when this approach is adopted for another system{{pmid|20005245}} | * A large number of subjects are required when this approach is adopted for another system{{pmid|20005245}} | ||
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| KDM | | KDM | ||
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* The calculation of KDM is complicated{{pmid|20005245}} | * The calculation of KDM is complicated{{pmid|20005245}} | ||
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