Methyl Donors: Difference between revisions

No edit summary
Line 6: Line 6:


There are several primary methyl donors in human physiology:
There are several primary methyl donors in human physiology:
 
{| class="wikitable"
# '''S-Adenosylmethionine (SAMe)''': Produced from methionine and ATP, SAMe is a principal methyl group donor involved in numerous methylation reactions. It’s vital for the synthesis of neurotransmitters, nucleic acids, proteins, and lipids.
|+
# '''Betaine (Trimethylglycine, TMG)''': Found in various foods like beets and spinach, betaine is involved in the conversion of homocysteine to methionine, donating a methyl group in the process.
!Methyl Donor
# '''Folate (Vitamin B9)''': Folate is central to the one-carbon metabolism cycle, where it assists in transferring one-carbon units for DNA synthesis and repair.
!Description
# '''Vitamin B12 (Cobalamin)''': This vitamin works closely with folate in the methionine synthase reaction, converting homocysteine back to methionine.
|-
|[[S-Adenosylmethionine (SAMe)]]
|Produced from methionine and ATP, SAMe is a principal methyl group donor involved in numerous methylation reactions. It’s vital for the synthesis of neurotransmitters, nucleic acids, proteins, and lipids.
|-
|[[Trimethylglycine (TMG)]]
|Found in various foods like beets and spinach, betaine is involved in the conversion of homocysteine to methionine, donating a methyl group in the process.
|-
|[[Vitamin B9 (Folate)]]
|Folate is central to the one-carbon metabolism cycle, where it assists in transferring one-carbon units for DNA synthesis and repair.
|-
|[[Vitamin B12 (Cobalamin)]]
|This vitamin works closely with folate in the methionine synthase reaction, converting homocysteine back to methionine.
|}
#


== Methyl Donors and Aging ==
== Methyl Donors and Aging ==