Resveratrol: Difference between revisions

Resveratrol (view source)

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 === Resveratrol with Piperine ===
-In <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910313/</ref> a double-blind, randomized, three arm pilot study was performed. Participants were randomized to receive a single dose of resveratrol 2500 mg, with piperine in 0 mg, 5 mg or 25 mg dose. Despite the observation of piperine coadministration significantly increasing bioavailability ([[Cmax|C<sub>max</sub>]] and [[AUC|AUC)]] of resveratrol in [[C57BL/6 mice|C57BL]] mice, no significant increase in resveratrol or decrease in resveratrol glucuronide could be observed in healthy adults taking 2.5 gm of resveratrol with piperine (5 or 25 mg) as compared to resveratrol alone.
+In 2021 a double-blind, randomized, three arm pilot study was performed. Participants were randomized to receive a single dose of resveratrol 2500 mg, with piperine in 0 mg, 5 mg or 25 mg dose. Despite the observation of piperine coadministration significantly increasing bioavailability ([[Cmax|C<sub>max</sub>]] and [[AUC|AUC)]] of resveratrol in [[C57BL/6 mice|C57BL]] mice, no significant increase in resveratrol or decrease in resveratrol glucuronide could be observed in healthy adults taking 2500 gm of resveratrol with piperine (5 or 25 mg) as compared to resveratrol alone. <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910313/</ref>
 === Micronized Resveratrol ===