Rats (Rattus Norvegicus): Difference between revisions
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[[File:SpragueDawleyRat.jpg|frameless|right]]'''Laboratory rats''' or '''lab rats''' are strains of the rat subspecies ''Rattus norvegicus domestica'' which are bred and kept for scientific research. While less commonly used for research than [[Mice|laboratory mice]], rats have served as an important animal model for research in psychology and biomedical science.<ref name="Vandenbergh">{{cite journal |last=Vandenbergh |first=J. G. |title=Use of House Mice in Biomedical Research |journal=[[ILAR Journal]] |date=1 January 2000 |volume=41 |issue=3 |pages=133–135 |doi=10.1093/ilar.41.3.133 |doi-access=free}}</ref> | [[File:SpragueDawleyRat.jpg|frameless|right]]'''Laboratory rats''' or '''lab rats''' are strains of the rat subspecies ''Rattus norvegicus domestica'' which are bred and kept for scientific research. While less commonly used for research than [[Mice|laboratory mice]], rats have served as an important animal model for research in psychology and biomedical science.<ref name="Vandenbergh">{{cite journal |last=Vandenbergh |first=J. G. |title=Use of House Mice in Biomedical Research |journal=[[ILAR Journal]] |date=1 January 2000 |volume=41 |issue=3 |pages=133–135 |doi=10.1093/ilar.41.3.133 |doi-access=free}}</ref> | ||
== Strains used in Longevity Research == | |||
{| class="wikitable" | |||
! Strain | |||
! Characteristics | |||
! Relevance to Longevity Research | |||
|- | |||
| Wistar | |||
| General-purpose strain, albino coat | |||
| Commonly used in aging studies due to well-documented lifespan | |||
|- | |||
| Sprague Dawley | |||
| Outbred, albino, large size | |||
| Popular for age-related disease studies | |||
|- | |||
| Brown Norway | |||
| Inbred, brown coat, long lifespan | |||
| Known for its exceptionally long lifespan, useful for studying aging processes | |||
|- | |||
| Fischer 344 | |||
| Inbred, albino, prone to certain age-related diseases | |||
| Frequently used in gerontology for studying age-related pathologies | |||
|- | |||
| Long-Evans | |||
| Outbred, hooded coat, good healthspan | |||
| Utilized in research focusing on the quality of life and health in old age | |||
|- | |||
| SHR (Spontaneously Hypertensive Rat) | |||
| Inbred, used in cardiovascular research | |||
| Valuable for studying the interplay between hypertension and aging | |||
|} | |||
== See Also == | == See Also == | ||
Revision as of 01:52, 8 December 2023
Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica which are bred and kept for scientific research. While less commonly used for research than laboratory mice, rats have served as an important animal model for research in psychology and biomedical science.[1]
Strains used in Longevity Research
| Strain | Characteristics | Relevance to Longevity Research |
|---|---|---|
| Wistar | General-purpose strain, albino coat | Commonly used in aging studies due to well-documented lifespan |
| Sprague Dawley | Outbred, albino, large size | Popular for age-related disease studies |
| Brown Norway | Inbred, brown coat, long lifespan | Known for its exceptionally long lifespan, useful for studying aging processes |
| Fischer 344 | Inbred, albino, prone to certain age-related diseases | Frequently used in gerontology for studying age-related pathologies |
| Long-Evans | Outbred, hooded coat, good healthspan | Utilized in research focusing on the quality of life and health in old age |
| SHR (Spontaneously Hypertensive Rat) | Inbred, used in cardiovascular research | Valuable for studying the interplay between hypertension and aging |
See Also
- Wikipedia - Laboratory rat
References
- ↑ Vandenbergh; "Use of House Mice in Biomedical Research" , https://doi.org/10.1093/ilar.41.3.133