2023-03-18 - Interview Dr. David Sinclair - India Today - Exclusive Conversation With Geneticist & Harvard Professor David Sinclair
- https://www.youtube.com/watch?v=fsUUgTPtwnc&ab_channel=BusinessToday
- Interviewer: Kalli Purie
- David Sinclair is a man who claims his ‘biological age’ is 10 years less than his actual age of 53. The Harvard Geneticist is a leader in longevity science. Watch him in a riveting conversation with Kalli Purie, Vice Chairperson, India Today Group at the #IndiaTodayConclave. The two discuss the formula to look younger, how healthy sugar is for you, whether fruits are a good substitute for sugar, the newly-researched stress-busting food, the benefits of red wine and the magic of metformin
Transcript
good afternoon everyone
we're fast coming to an Era where we
will be celebrating our DNA age and not
our birth age
our birthdays will mean we get younger
and not older imagine that
I have with me
the handsome Miracle almost 54 year old
doctor from Howard Middle medical school
who specialized in molecular genetics
he promises no aging no wrinkles no
disease and possibly choosing your own
death date
author of lifespan and professor of
genetics
welcome there are many beautiful people
here today in the audience but Everyone
likes a few tips right
so first of all can you explain to the
audience here what is the basic theory
of
reversing aging and bio switches
well thank you Kali thank you for having
me today
uh so the science of aging and aging
reversal has come a long way in the past
20 years
uh when I started at Harvard Medical
School it was considered crazy to try
and slow down aging let alone reverse it
but the science is now at a point where
we really do understand
what drives aging and also that there's
a backup copy of Youth in every one of
our many trillions of cells that we've
just recently learned how to access and
reboot the body like you would reboot an
old computer
and reinstate the youthfulness of
tissues
and organs and make them work again like
they were young and this is only a few
years old now but it's the technology is
far beyond what I thought I would see in
my lifetime and it's only getting faster
in its development
so can you explain the basic Theory
which is about keeping the body under a
state of constant stress to activate the
longevity genes how does that work
Yeah you mentioned the bio switches what
we discovered in my lab and in many labs
around the world
that is that there are genes that
control how long we live
some of us are born with
the best versions of those genes and
those people tend to live over a hundred
those with parents like the Prime
Minister that lived over 100 I tend to
live also for a long time but most of us
are not born with the perfect set of
genes so we need to do a little extra
and what we've discovered is that how we
live our life what we eat how much we
move the type of molecules that we
ingest every day how we sleep how
relaxed we are how many friends we have
this modifies another type of system in
the body
that's called the epigenome the
epigenome is different from the genome
I think you all know that the genome is
the DNA that we get from our parents the
epigenome is what controls the DNA that
tells a brain cell to be different from
a liver cell from a toenail producing
cell
and over time we lose those instructions
the epigenetic instructions
become lost
and what we've found is that by living a
healthy life
the kind of life that we'll talk about
later you can slow that rate of Aging
and prevent this this Corruption of the
body software
and even reboot it
so can we talk a little bit about this
style of living what are the things that
we can do to slow that aging process
down and activate these genes
yeah well there's there's some good and
bad news the good news is that aging is
much easier to slow and reverse than we
thought
the bad news is that what causes us to
slow our aging process is to give our
bodies a bit of a shock
in today's lifestyle most of us have an
abundance many of us we have enough food
and we don't need to exercise
that's not the way we used to live and
it's not the way our bodies perform the
best
by sitting for most of our lives and
eating almost you know constantly three
meals a day for many of us we end up
turning off these body switches and the
body ages faster and faster so we've
built a world that's very comfortable
but the backlash is that we age faster
so what we've discovered in my lab in
studies in yeast cells that make bread
and beer in worms and flies and mice and
monkeys and now humans is that we want
to put our bodies into a state of
adversity make the body feel a little
bit uncomfortable so how do we do that
well we can skip meals we can exercise
we can eat food that it's that is
plucked from the ground when it's also
stressed because they have wonderful
chemicals in them that make us healthier
and we can also get enough rest and calm
down the sleep that leads to
inflammation and other things like that
so really you want to make your body
fearful of running out of food or
fearful that you're having to run away
from a from a tiger and that turns on
the body's defenses against aging we've
learned but that doesn't reverse aging
so much that's requires a little bit
more attention which we've only recently
figured out how to control
and before
can we talk a little bit about skipping
meals what what do you recommend as a
diet
for slowing down the aging process
there is a set of genes that I wrote
about in my book lifespan that's called
the sirtuins and they get turned on when
there's not enough energy in the body so
if you don't have a lot of sugar in your
bloodstream or a lot of protein they
will get turned on and they defend the
body against the damage that causes the
the aging process and so what I've over
time learned to do is to skip meals I'm
not always successful
sometimes I have breakfast in in uh in
beautiful places but from my my goal is
to not eat a large meal until dinner
and then I eat a very healthy vegan meal
uh and very rarely alcohol and this diet
that I have gone on to for now about 18
months my partner Serena poon who's a
nutritionist and a longevity expert as
well
moved me from what I thought was a
healthy diet Mediterranean diet with
some red wine and cheese I went
completely to mostly well almost
completely to plants and my body has
responded I look better I think my skin
is better I feel better my memory is
certainly better
but I think it's not just what you eat
it's also when you eat and this constant
eating three meals a day plus snacks is
making us age faster than we need to
so are you recommending intermittent
fasting
well the way we put it Serena and I is
you want to eat within a certain window
and so I like to eat within a period of
about six hours a day and not more I can
snack you know some snacks might be some
sugar-free chocolate or some nuts or
some avocado it's not a crime to eat if
you're a little bit hungry but don't eat
a big meal and if you can until either
late at night or or have it in the
morning because you want to have a
period where your body is not ingesting
food and it will turn on its defenses
against disease and aging see can you
talk a little bit about the fact when
you went almost 20 hours without eating
and you did that for a period of time
yeah so 20 hours is a long time to go
without food every day but your body
gets used to it I found that after two
weeks of doing that I was not hungry
anymore if I felt a little bit hungry I
would drink a lot of tea Serena and I
have a green tea matcha which is filled
with all these wonderful chemicals from
stress plants
and drink drink a lot of water and tea I
think here in India we know how to do
that
and that is the solution and
we often think oh we need to feed the
body the sugar that you know have a
dessert have a have some some lollies
but really your body can make its own
sugar your liver makes sugar you just
need to wait two weeks for it to get
used to it our liver is pretty lazy but
after two weeks it learns ah in the
morning I have to make some sugar and
what what I found is that my liver
making sugar is a lot smarter than my
eyes and my mouth eating sugar because
when we eat three meals our sugar goes
up and down and up and down and we get
we get lots of energy then we crash and
we get brain fog and then we need eat
again and we're hungry and you go like
this through the day when you don't eat
until dinner
your steady with your sugar because your
liver knows what to do and you can focus
and just have a lot of energy
so one meal a day
um you would recommend that and what
would you recommend in that one meal
yeah well try to eat and try to at least
skip one meal a day that would be my
recommendation and if you can do two
even better some people go without food
for three days I've never been able to
do that I like food
but what's in the food well as I
mentioned I went from drinking a lot of
red wine because
red wine actually that the component of
red wine Resveratrol was discovered in
my lab to slow aging so I thought drink
a lot of red wine that's got to be
healthy but the new research just over
the last two years says that alcohol
drinking drinking alcohol every day is
really not good for you so I've cut out
alcohol and I've focused on Plants so
this vegan diet has no Dairy which is
very difficult here in India yes uh but
we we do that we substitute milk with
coconut and nut based milks and yogurts
they taste very good as well and then so
a typical dinner would be
well plant-based meals that that taste
just or even better than what I used to
eat and I don't feel like I'm lacking
anything and you might ask well why
would you do that well there's a lot of
science behind it
the Protein that's in plants is actually
has a ratio of amino acids that
stimulates these longevity genes the
septuans and another one called mtor and
if you always eat meat every meal your
body is just not fighting aging the way
it could if you ate more plants
so you're against meat in that sense
well I love meat I would love to eat
meat they taste it tastes really good
it's just the science says plants give
you better bang for the Bark for
longevity than meat I mean you can eat
meat occasionally fish for example has a
lot of great omega-3 fatty acids
um so I'm not against meat I just think
try to focus more on plants if you can
you say you said something about
stressed vegetables okay you talk a
little bit about that what is that
versus you know normal organic
vegetables
yeah so when Farmers grow vegetables
they try to grow them as fast as
possible
it's much more economical the problem
with that is that giving plants a lot of
sunlight and water and fertilizer
makes them very happy
and as I just told you a happy organism
does not is not a healthy organism so
when plants have a little bit of stress
so a little bit of lack of water or
there's a little bit of a caterpillar on
there or even not a lot of sun in the
case of green tea matcha they put the
plants in the shade then those plants
respond in a stress response they turn
on the production of chemicals
called polyphenols Resveratrol from red
wine is a polyphenol that's produced
when the plants get stressed and it's my
theory
which has a name a terrible name I
apologize it's called Xeno hormesis
zenor means I was hoping you were not
going to bring it up because of the
terrible name yeah well just remember
eat if your food is stressed then you
get the benefits
stress your food so you don't have to
and so what we focus on Serena and I are
plants that are full of color Serena
says eat the rainbow so try to eat
bright red and purple dark green colored
vegetables because those are the ones
that have these polyphenols that can
turn on the body's defenses and actually
in my lab if we give polyphenols to mice
they actually get healthier and run
further like they've been exercising so
these little molecules polyphenols can
actually
not substitute but can help you with
your exercise and your otherwise healthy
plant diet so in Superstores we're going
to have inorganic organic and stressed
vegetables now
that's a great business plan we should
do that
sugar sugar
is very addictive of and it's a real
pick me up so is there a healthy way to
have sugar
uh depends on the sugar if you're
talking about cane sugar sucrose I would
try to limit that as much as possible
unfortunately I gave up eating
desserts in my 40s though I do steal it
from people at the table so Serena
orders the desserts for me but really
sugar is something that is known to be
toxic in the long run it's
sucrose which forms glucose will attach
to your your body's components your
proteins will become what's called
glycated and that's known to drive aging
as well so that's why we try to not eat
too much and so we don't want to eat a
lot of sugar but there are substitutes
there's for example monk fruit produces
sugar which Serena has told me to try
and it tastes just as good as sugar and
it doesn't give you that Spike and that
should be good for longevity what about
Stevia maple syrup honey coconut sugar
um they're all on a various scale um
honey has is not so good in large
amounts Stevia I think is okay but it's
all on a scale I think the best is
allulose or monk fruit and then a bit
above that a bit worse than that is
Stevia but at the bad end is glucose
sucrose and honey but honey has a lot of
good goodness in it so I wouldn't say
avoid honey just don't eat too much of
it
how would you classify sugar and fruit
like would that be something you would
stand replace desserts with like at the
end of a meal would you just have a
piece of fruit yeah for sure fruit is
good
um I would avoid fruit juices unless
they're from fruits that don't have a
lot of sugar but oranges and apples and
pineapple have a lot of sugar that I
generally avoid
okay
um I'm going to talk to you a little bit
about your Vitality pills
why don't you tell us a little bit about
the Vitality pills and what we can do to
make ourselves you know
eternally Young and Beautiful yeah
so I I've been taking supplements for
and experimenting on myself for about 20
years and my father has also been doing
it he's now 83 and in perfect health
and what I learned through my research
and through my own
self-explanation and then clinical
trials in hospitals is that there's
certain molecules from Mostly from
plants that provide the benefits of
fasting and exercise as well
and so I was taking these separately I
take a variety of them
do you want me to go into which yes I
mean don't go into the details but we
would all like to know where these pills
are available and what's in them sure
everyone's thinking where can I get the
prescription all right so if you don't
have a pen uh you can go to my book and
I wrote these chemicals these
supplements down in my book in the
English version it's page 304.
um and there are three main things that
I take and have taken for over a decade
the the one chemical that I take every
day is Resveratrol which is the red wine
chemical and that comes from grapes
and so that one gets sprinkled into some
yogurt in the morning
I also take a moment that's the one
where which which red wine has right but
it's the amount you take is equivalent
to
750 glasses of red wine per day
I don't recommend getting it from red
wine
uh
so the the other molecule is called nmn
nmn not to be confused with M M's don't
don't mix those up nmn is a a version of
vitamin B3 that makes a chemical in the
body that we need for life and that's
called NAD and as we get older we make
less and less of this and without NAD
these sirtuins that we discovered slow
aging remember the genes that we
discovered they don't work without a lot
of NAD so as we get older our defenses
Decline and so by taking this supplement
we know that it doubles the levels of
NAD back to when I was age 20. and
there's now clinical trials that my
colleagues at Harvard have done that
says that nmn has some health benefits
in early studies such as lowering
cholesterol and blood pressure and so I
take that one every day as well
um I take a half a gram of that
currently and then the third one is
metformin metformin is a little bit more
controversial because it's a drug
and it's just classified as a drug and
uh that doesn't mean it's necessarily
dangerous in fact it's one of the
world's safest drugs it's used for type
2 diabetes to control blood sugar
and what's been found is that people who
take Metformin tend to live a lot longer
even those who don't have type 2
diabetes there's evidence that they are
protected against
cardiovascular disease and Frailty and
even Alzheimer's disease and so what I
do is I take metformin even though I
don't yet have type 2 diabetes
so metformin is it a form of this glp-1
receptor blockers a skinny pen orozmic
which all of Hollywood is apparently on
and they're getting thinner and thinner
if you see the red carpet at Oscars is
that what it is a form of that well no
it's actually very different metformin
will activate your body's energy
production and boost mitochondria which
are the little energy packs in your
cells so that's that's a healthy way to
do it uh I won't say the brand name but
yeah this GOP one agonistar
um causing your body to become more
insulin sensitive and take up the sugar
from your blood and burn fat and people
who take this drug uh it's uh they
actually they do lose weight
um
so the it I mean the drug is designed to
treat type 2 diabetes and it's it's
actually a blockbuster very effective
drug one of my colleagues over uh in New
York near barzalai says that in his
practice he essentially now thinks of
type 2 diabetes as a curable disease
only in the last few years because of
these new drugs but people who don't
have obesity or diabetes are taking it
or they might have obesity but they
certainly don't have type 2 diabetes and
they lose weight the one negative side
effect that everyone should be aware of
is that people can lose too much fat in
the wrong place including in the in the
face where you don't want to lose it
especially if you're older and you can
tell if somebody's taking this medicine
because they start to look it's called
the brand name face right I'm not taking
the brand name either but that's what
it's called yeah it is so you have to be
very careful I would say it's much
better to eat less often and exercise
and you'll get much bigger health
benefits than taking that drug let's
talk a little bit about exercise what
kind of exercise are you recommending
like a lot of intro training running
Strength yoga
you know yoga is very important uh I
think here are you just saying that
because Serena is sitting opposite us so
yeah screen is down there
below the stage here so Serena is um the
equivalent of me with more of a practice
and knowledge about yoga and nutrition
and mind and body and I missed I missed
the biology and chemicals but together
we we we do recommend a lot of
stretching and yoga meditation to reduce
stress though I'm not I'm not good at it
and I'm also not good at exercise I'm
often on planes Serena and I have been
traveling for two months now so we don't
get a lot of exercise in
that said I used to and what I used to
do was to exercise three times a week
and Lose My Breath you want to be able
to be moving so fast that you cannot
carry out a conversation easily that's
when you know you're becoming
hypoxic low in oxygen and this low
oxygen we think is a very good
stimulator of this
stress on the body and it your body
responds in a positive way to build
muscle get better blood flow and also
your tissues will put out chemicals that
slow aging so really if you can just
lose your breath for 10 minutes three
times a week that can give Remarkable
Health benefits lowering the rates of
disease by 30 percent
so a little bit goes a long way can we
get a mic to Serena
so Serena is a proponent of yoga and I
want to know what she thinks about that
because in yoga you don't necessarily
stress the body to a point where you
lose your breath or you get out of
breath
[Music]
types of Yoga yoga of course especially
in the U.S I'm based in La there's yoga
that is used more as a form of exercise
and that can be quite stressful in the
body
I think we stress our bodies in a
slightly different way when it comes to
yoga because we're really stressing our
mind
you know it's really about uh
how how long you can hold still
how you can clear your mind how you can
hold a pose that's stress in a different
way it's really more stress on the Mind
whereas Dave is talking about the
stresses on the body but effectually it
will still have the same results so and
David can share about that so we're
looking for that balance in a way where
we're balancing our body but there is a
stress to our mind and getting to that
stress point is then where we find
balance
so you two are from two opposite ends of
the Spectrum in a way you move from a
western school of thought she's moved
from an Eastern school of thought what
are the things that you guys agree on
over the dinner table and what are the
things that you don't agree on
yeah it people wonder how do we get
along because uh I'm opposites
attractive 100 reality and Serena is
very spiritual uh but but we we bonded
over uh our love for health uh and
wellness and respect for the human body
we both believe that we can help
Millions if not billions of people live
healthy and longer lives with our
message that covers both eastern and
western what do we agree on we agree on
nutrition
um basically because I do whatever
Serena tells me to do
uh but what we disagree on are things
like
um
how
how important is
uh
the the spiritual side of life I
struggle trying to believe in things
that I have no evidence for and Serena
has a lot of faith uh and she's always
right so I think she's onto something
um
we tend not to disagree on a lot of
things I think our interpretation of How
It's Working is different I will say oh
well it's this molecule it's this
molecule and she says no it's that the
body has different energies and it's
working this way and according to
aerobatic practices this is how it's
working
well it it really is it's a it's a
wonderful combination the two of us
because we we learn from each other and
often we we end up with a
an explanation for phenomena that
includes both old and new science
that's a very
that's a core practice that uh
David sort of dabbles in a little bit
doubles in means what like two minutes a
day or I don't know honey how many how
much do you meditate a day well my
problem is I I try to meditate and I
always fall asleep and yeah
I start snoring so I'm not good at
meditation what I found instead works
for me is to have quiet time we call it
I close my eyes for 11 minutes uh
hopefully at least twice a day and have
some gratitude during that quiet time or
listen to someone talking about stoicism
that's what I like to do I struggle with
meditation I will admit with my crazy
lifestyle and my lack of commitment to
that I haven't been successful really
but I really should be because the
benefits on controlling your mind have
been proven I like to talk about animal
studies so in mice if you modify the
Mind Of Mice so you can change parts of
the brain of a mouse you can actually
improve immunity improve health even
make the mice live longer just by
changing parts of the brain it's very
clear that if you can control your mind
calm it down get it to focus
have the positivity as well you can have
Whole Body Benefits that are often
misunderstood by Western person
so with some of the things that you're
suggesting um which are not by the way
easy going 20 hours without food or you
know giving up sugar we differ too
you differ there what what is it that
well I'm I'm more about eating within a
window which David share that we we talk
about eating Windows uh
so you're
you know which may mean more than one
meal a day so you can fast for 12 hours
or 14 or 16 or 18 or David can go to 20.
uh but it's really about making sure you
get the nutrients that you need for your
body during that window of time that you
do eat
and my belief more than trying to cram
everything into one meal so we differ
just slightly on that as well
so we have um you know there's a lot of
pressure to look good and nobody else
has that pressure more than people who
are in a public space we have a few
actors here who are coming in from a hit
Ott show called the class you can see
all all the very brightly dressed
fashionable people right here up in
front
um I'd like to ask them how tough is the
pressure on you guys to look good and
what are the extreme things you've done
I think uh it's it's huge I a lot of us
had to de-age essentially for the
character and what you were saying about
losing breath or being out of breath I
chanced upon accidentally because while
I was
uh working out for the role I was boxing
like four times a week and I found that
I genuinely like now when people ask me
they're like oh we can't guess your age
I can't believe you're so much less
older than you she's not giving her age
away
uh no but but it genuinely I feel like
we kind of chanced Upon A lot of the
things you spoke about today and they're
all making sense now
I think I'm gonna hate me for this but I
had fruits for like two years straight I
was on a fruitarianism diet I don't know
if you know there's the Robert Moore's
concept of raw vegan diet so I was on
that and I still sort of follow it not
exactly because now I have temptations
and I go and have something whatever I
need but mostly I used to drink a lot of
juice uh and still in the morning I had
like I think a liter of juice from the
hotel itself and they were like your
wife just drinking you have a drinking
problem of juice so yeah so that was one
thing with me so I I just wanted to know
your version one thing if I ca if I may
please most of the things that you said
and most of the things out there
everything revolves around one thing and
that is uh firstly uh separating your
body from mucus like the mucus we
produce due to eating a lot of cooked
Foods
one thing that hasn't been resolved yet
is the uh the male pattern baldness
because even in fluterine is uh in the
fruit diet nobody has actually given a
solution to that so look at David's hair
just look at David's hair yeah exactly
that's why I was asking because I want
people to this yeah I want this hair
yeah so yeah
yeah well I I think I'm lucky
um but I also think that if you slow
your body's body's aging your hair will
also slow down in its changes I I don't
yet have much gray hair
um I I will admit my mother also had
good hair so it might be that uh but
there's a lot of really good signs going
on in fact Serena and I have
co-developed a product that uh is was
developed for the skin in collaboration
with NASA
um and it has this uh space resistant
organism extract in it called bacillus
lysate and the clinical trials so far
are showing hair regrowth I don't think
it's it's crazy to think in five years
it'll be common to be able to get your
hair back
um just by spraying something on the
science is there what we're doing in my
lab is we can grow skin and hair
artificially in the dish from stem cells
and we can age that skin forwards and
then reverse the age and we're looking
for ways to do that with natural ways to
do that so that we can put it into a
cream that you could put on the hair and
not just make your hair look better but
actually make your whole skin on your
head literally be younger than it used
to be and that's what I want to do is to
make the body not just look younger but
literally be younger
so you know a question comes up from
there that if we reboot reboot our body
to let's say
in
does our mind reboot to 16 or 21 as well
I mean am I going to have the same sort
of intelligence creative
urges as a 21 year old or a 16 year old
uh well Serena says sometimes I I get
too young uh but there's a there's a
happy ending what do you do when you get
too young do you get frisky do you want
to go dancing or what do you do
uh you know what young men are like
they're a little bit um
a little bit immature
no don't don't give Serena the mic I
tend to be a little bit uh
uh over enthusiastic let's say about
things and and I've learned to to calm
my decision making and be be less
reactive
in all seriousness what we're doing now
in my lab at Harvard is
um so what we do is to reverse aging is
we put we we turn on three genes that
are normally only turned on in very
young
uh embryos so when we're young we when
we're just born or before we we are very
young and we stay young because there
are three genes that are turned on
they're called O S and K for short
and when we turn on these three genes in
the adult tissue
in human adult tissue or in a mouse
those three genes make the body younger
again this is the reset of the software
and uh and we can do that not just with
uh the eyes and cure blindness which we
did a couple of years ago we recently
published in January that we could
rejuvenate
a whole Mouse and and see aspects of
Aging reversed
um and so that's where we're going is to
truly do a full age reset
now what we're doing is asking what
happens if you reset the age of the old
brain and we can grow human brain in the
lab if you looked on my Instagram
account you can see little pictures of
human brains that we grow we can make
them old throw them make them old in
about a month make them 70 years old in
a month and then we can reverse that we
can give them Alzheimer's disease see
what happens and if we reverse it so
here's the punch line if we reverse the
age of an old Mouse's brain to make it
much younger by 70 it gets its ability
to learn back again and we're now just
testing if it also remembers lost
Memories We don't know the answer but we
hope to find out soon so we may have a
situation where teenagers are world
leaders and running the whole economy
and every space I don't know what kind
of decisions they would make then I mean
teenagers are great teenagers are great
but I don't know whether we want them to
be running the world we just have a
minute a minute left
um I wanted to get a little bit into
this philosophical and spiritual
areas with anti-aging and age reversal
um we are in India we have an ancient
concept of Karma and God's will and here
you are creating a space where nobody
needs to suffer or at least the rich
don't need to suffer and they can choose
their day to die are you playing God
doctor
I don't think that I am I think that
the pursuit of health
and wellness and happiness
is a natural human endeavor and it's a
very noble cause
and I'm not
on this Earth to make people live
forever
I believe my mission and with Serena our
mission is
to increase the advances extend the
advances that we made last century with
medicine
but to make it even more effective so
that with one treatment we don't just
treat cancer we can treat all the other
diseases that affect us by making us
younger and fitter
I don't believe that's playing God any
more than developing
treatments for cancer and heart disease
and dementia is playing God
and I think as humans we've always
wanted to live better we've wanted to
modify our environment modify our bodies
to be happier and healthier what part of
this room is natural I I don't think
make even this I think is artificial so
we as humans we adapt we change our
environment and this is the next step in
human evolution and I think it's the
right step because we all have a right
to decide how healthy we are we can't
choose when we were born but I hope that
one day we'll have a choice when we die
what age would you like to
well it's a strange question to ask but
how what age would you like to die
um I think the answer would be uh not
tomorrow and and that will always be the
case if you're healthy and happy and
have friends uh you'll never want to die
I just I know this as a human uh a trait
and so really the answer is as long as
possible but I'd be happy with another
40 years to do more good work
that would be like a hundred
I hope more what's happening we talk
about AI at this Symposium the rate of
change in this field is going up
dramatically and so the advances that we
can make now with the assistance of AI
is dramatic and in our lifetimes we are
truly going to see the ability for our
doctors to give us medicines that
reverse our age and we can do that
multiple times and so it's an extremely
exciting time to be alive and stay alive
thank you so much doctor
so in conclusion I think basically we
need to trick our body into thinking
we're almost dying so that we can live
longer and all those people who give me
trouble for causing them stress hey I'm
helping you live longer
and I hope that after this chat about
skipping meals oh I obviously I'm giving
stress to a lot of people here you can
hear the claps right
um uh after this chat I hope that you're
going to make different choices at lunch
maybe even skip lunch the doctor is
going to be available at lunch he's
definitely not eating any lunch so you
can bomb him with some of your questions
I'm sure some of you have those and
thank you very much doctor for being
here and helping us through this process
and here's to all of you choosing your
own day to die
thank you thank you
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