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|{{pmid text|36443648}} | |{{pmid text|36443648}} | ||
|6 weeks, lifestyle modifications | |||
* no NMN (n=10) | |||
* 800 mg/day (n=9) | |||
| | | | ||
* 19 mild hypertensive adults | |||
* age 18-80 | |||
| | | | ||
* Supplementing hypertension patients with 800 mg of oral NMN per day for six weeks significantly lowers their blood pressure. | |||
* Hypertension patients display significantly lower blood cell NAD+ levels, and taking NMN increases their blood cell NAD+ levels by ~43%.. | |||
* Adults with hypertension have cells lining blood vessels — endothelial cells — with elevated concentrations of the NAD+ consuming enzyme CD38, which partially explains their lower NAD+ levels. | |||
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