Xenohormesis: Difference between revisions

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	'''Xenohormesis''' is a hypothesis that posits that certain molecules such as plant polyphenols, which indicate stress in the plants, can have benefits of another organism (heterotrophs) which consumes it. Or in simpler terms, xenohormesis is interspecies hormesis. The expected benefits include improve lifespan and fitness, by activating the animal's cellular stress response.{{pmid\|~~184559760~~}}		'''Xenohormesis''' is a hypothesis that posits that certain molecules such as plant polyphenols, which indicate stress in the plants, can have benefits of another organism (heterotrophs) which consumes it. Or in simpler terms, xenohormesis is interspecies hormesis. The expected benefits include improve lifespan and fitness, by activating the animal's cellular stress response.{{pmid\|18455976}}

	The term xenohormesis was first coined by Kondrad T. Howitz and [[David A. Sinclair]], in the 2004 paper "Small molecules that regulate lifespan: evidence for xenohormesis".<ref>{{cite journal\|last1=Lamming\|journal=Molecular Microbiology\|s2cid=18803431\|pmid=15306006\|doi=10.1111/j.1365-2958.2004.04209.x\|pages=1003–1009\|issue=4\|volume=53\|url=https://semanticscholar.org/paper/df2808b38be6a75089b01b46b19920b455229a04\|first1=Dudley W.\|title=Small molecules that regulate lifespan: evidence for xenohormesis\|date=16 July 2004\|first3=David A.\|last3=Sinclair\|first2=Jason G.\|last2=Wood\|doi-access=free}}</ref> ''Xeno'' comes from greek, meaning foreign, and hormesis is the adaptive response of organisms and cells to stress.<ref name=":02">{{Cite web\|last1=Howitz\|first1=Konrad\|last2=Sinclair\|first2=David\|date=2008\|title=Xenohormesis: Sensing the Chemical Cues of Other Species\|url=https://www.cell.com/cell/fulltext/S0092-8674(08)00511-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867408005114%3Fshowall%3Dtrue\|access-date=April 28, 2023\|website=Cell}}</ref>		The term xenohormesis was first coined by Kondrad T. Howitz and [[David A. Sinclair]], in the 2004 paper "Small molecules that regulate lifespan: evidence for xenohormesis".<ref>{{cite journal\|last1=Lamming\|journal=Molecular Microbiology\|s2cid=18803431\|pmid=15306006\|doi=10.1111/j.1365-2958.2004.04209.x\|pages=1003–1009\|issue=4\|volume=53\|url=https://semanticscholar.org/paper/df2808b38be6a75089b01b46b19920b455229a04\|first1=Dudley W.\|title=Small molecules that regulate lifespan: evidence for xenohormesis\|date=16 July 2004\|first3=David A.\|last3=Sinclair\|first2=Jason G.\|last2=Wood\|doi-access=free}}</ref> ''Xeno'' comes from greek, meaning foreign, and hormesis is the adaptive response of organisms and cells to stress.<ref name=":02">{{Cite web\|last1=Howitz\|first1=Konrad\|last2=Sinclair\|first2=David\|date=2008\|title=Xenohormesis: Sensing the Chemical Cues of Other Species\|url=https://www.cell.com/cell/fulltext/S0092-8674(08)00511-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867408005114%3Fshowall%3Dtrue\|access-date=April 28, 2023\|website=Cell}}</ref>