2,851
edits
Hallmarks of Aging: Difference between revisions
→The Hallmarks in Detail
| Line 187: | Line 187: | ||
|Telomere shortening is associated with a variety of human diseases, including pulmonary fibrosis, dyskeratosis congenita, and aplastic anemia, often linked to deficiencies in telomerase or shelterin components{{pmid|22965356}}. | |Telomere shortening is associated with a variety of human diseases, including pulmonary fibrosis, dyskeratosis congenita, and aplastic anemia, often linked to deficiencies in telomerase or shelterin components{{pmid|22965356}}. | ||
|- | |- | ||
| style="text-align:center; background-color:hsla(180, 100%, 85%);" |[[File:Epigenome-transparent-upscale.png|frameless|85x85px]] | | rowspan="3" style="text-align:center; background-color:hsla(180, 100%, 85%);" |[[File:Epigenome-transparent-upscale.png|frameless|85x85px]] | ||
| style="background-color:hsla(180, 100%, 85%);" |'''Epigenetic alterations''' | | rowspan="3" style="background-color:hsla(180, 100%, 85%);" |'''Epigenetic alterations''' | ||
| style="background-color:hsla(180, 100%, 85%);" | | | style="background-color:hsla(180, 100%, 85%);" |'''Histone modifications''': | ||
| | |||
| | |||
| | |||
| | |||
|- | |||
|'''DNA methylation''': | |||
| | |||
| | |||
| | |||
| | |||
|- | |||
|'''Chromatin remodeling''': | |||
| | | | ||
| | | | ||