2,851
edits
Oxidative Stress: Difference between revisions
→Antioxidants and Their Role in Combating Oxidative Stress
| Line 20: | Line 20: | ||
*'''Nucleic Acids:''' ROS, especially hydroxyl radicals, can cause oxidative damage to DNA, leading to mutations, strand breaks, and DNA-protein cross-linking, contributing to genome instability and cell death.{{pmid|31733333}}{{pmid|8379000}}{{pmid|23417673}}{{pmid|10720713}}{{pmid|12796402}}{{pmid|2545260}} | *'''Nucleic Acids:''' ROS, especially hydroxyl radicals, can cause oxidative damage to DNA, leading to mutations, strand breaks, and DNA-protein cross-linking, contributing to genome instability and cell death.{{pmid|31733333}}{{pmid|8379000}}{{pmid|23417673}}{{pmid|10720713}}{{pmid|12796402}}{{pmid|2545260}} | ||
== Antioxidants | == Antioxidants == | ||
'''Antioxidants''' are compounds that can prevent or slow down the oxidation of other molecules. Oxidation is a chemical reaction that can produce free radicals, leading to chain reactions that may damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates and inhibiting other oxidation reactions. They do this by being oxidized themselves, making them crucial in the body's defense against oxidative stress.{{pmid|28441057}} | '''Antioxidants''' are compounds that can prevent or slow down the oxidation of other molecules. Oxidation is a chemical reaction that can produce free radicals, leading to chain reactions that may damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates and inhibiting other oxidation reactions. They do this by being oxidized themselves, making them crucial in the body's defense against oxidative stress.{{pmid|28441057}} | ||