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S-Adenosylmethionine (SAMe): Difference between revisions
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# '''Methylation''': SAMe donates a methyl group in numerous methylation reactions. After donating its methyl group, SAMe gets converted to S-adenosylhomocysteine. | # '''Methylation''': SAMe donates a methyl group in numerous methylation reactions. After donating its methyl group, SAMe gets converted to S-adenosylhomocysteine. | ||
# '''Transsulfuration''': SAMe is part of the cycle that helps regenerate the amino acid methionine and also contributes to glutathione synthesis, a critical antioxidant in the body. | # '''Transsulfuration''': SAMe is part of the cycle that helps regenerate the amino acid methionine and also contributes to glutathione synthesis, a critical [[Antioxidant|antioxidant]] in the body. | ||
# '''Aminopropylation''': SAMe is involved in the synthesis of certain neurotransmitters and the formation of nucleic acids, proteins, and phospholipids. | # '''Aminopropylation''': SAMe is involved in the synthesis of certain neurotransmitters and the formation of nucleic acids, proteins, and phospholipids. | ||
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# '''Liver Health''': Aging is associated with a decline in liver function, and SAMe has been researched for its potential benefits for liver health, given its role in producing and breaking down various molecules in the liver. | # '''Liver Health''': Aging is associated with a decline in liver function, and SAMe has been researched for its potential benefits for liver health, given its role in producing and breaking down various molecules in the liver. | ||
# '''Neurotransmitter Synthesis''': SAMe is involved in the synthesis of several neurotransmitters. As neurotransmitter imbalances are linked to mood disorders and cognitive decline in older adults, maintaining optimal SAMe levels might have neuroprotective effects. | # '''Neurotransmitter Synthesis''': SAMe is involved in the synthesis of several neurotransmitters. As neurotransmitter imbalances are linked to mood disorders and cognitive decline in older adults, maintaining optimal SAMe levels might have neuroprotective effects. | ||
# '''Antioxidant Support''': Through its role in the transsulfuration pathway, SAMe is involved in the production of glutathione, one of the body's primary antioxidants. As oxidative stress is a significant contributor to aging and age-related diseases, SAMe's connection to glutathione synthesis becomes even more critical. | # '''[[Antioxidant]] Support''': Through its role in the transsulfuration pathway, SAMe is involved in the production of glutathione, one of the body's primary antioxidants. As [[Oxidative Stress|oxidative stress]] is a significant contributor to aging and age-related diseases, SAMe's connection to glutathione synthesis becomes even more critical. | ||
== Supplementation and Safety == | == Supplementation and Safety == | ||