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Nicotinamide Mononucleotide (NMN): Difference between revisions
Nicotinamide Mononucleotide (NMN) (view source)
Revision as of 02:56, 21 September 2023
, 21 September 2023→Combining NMN with Methyl Donors
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The potential concern is that excessive NMN supplementation might lead to a decrease in the body's available methyl groups, which play crucial roles in various biological processes including DNA methylation and neurotransmitter synthesis. | The potential concern is that excessive NMN supplementation might lead to a decrease in the body's available methyl groups, which play crucial roles in various biological processes including DNA methylation and neurotransmitter synthesis. | ||
For that reason, some individuals who take NMN also supplement with [[Trimethylglycine (TMG)]], a [[Methyl Donors|methyl donor]], to ensure that they are not depleting their body's methyl groups. However, this is a precautionary measure and not necessarily based on concrete evidence. | For that reason, some individuals who take NMN also supplement with [[Trimethylglycine (TMG)]], a [[Methyl Donors|methyl donor]], to ensure that they are not depleting their body's methyl groups. However, this is a precautionary measure and not necessarily based on concrete evidence. [[NOVOS]] use B vitamins and phosphatidylcholine as methyl donors in their product to avoid the side effects of TMG and because they think that TMG is already too deep into the methylation pathways, not allowing the body to choose the amount of methylation for itself. <ref>https://novoslabs.com/frequently-asked-questions/nmn-nicotinamide-mononucleotide/do-you-need-to-combine-nmn-with-tmg-trimethylglycine/</ref> | ||
However, there are a few important points to consider: | However, there are a few important points to consider: | ||