Sirtuins: Difference between revisions

28 bytes added ,  23 September 2023
no edit summary
No edit summary
No edit summary
Line 10: Line 10:
!Description
!Description
|-
|-
|SIRT1
|[[SIRT1]]
|Found primarily in the cell nucleus, SIRT1 is involved in DNA repair, gene expression regulation, and various metabolic processes.
|Found primarily in the cell nucleus, SIRT1 is involved in DNA repair, gene expression regulation, and various metabolic processes.
|-
|-
|SIRT2
|[[SIRT2]]
|Predominantly found in the cytoplasm, SIRT2 regulates cell cycle progression and is associated with maintaining cell integrity.
|Predominantly found in the cytoplasm, SIRT2 regulates cell cycle progression and is associated with maintaining cell integrity.
|-
|-
|SIRT3, SIRT4 and SIRT5
|[[SIRT3]], [[SIRT4]] and [[SIRT5]]
|These sirtuins are primarily located in the mitochondria and are pivotal for maintaining mitochondrial function, energy production, and metabolic homeostasis.
|These sirtuins are primarily located in the mitochondria and are pivotal for maintaining mitochondrial function, energy production, and metabolic homeostasis.
|-
|-
|SIRT6
|[[SIRT6]]
|Operating within the cell nucleus, SIRT6 plays a crucial role in DNA repair, genome stability, and metabolic regulation.
|Operating within the cell nucleus, SIRT6 plays a crucial role in DNA repair, genome stability, and metabolic regulation.
|-
|-
|SIRT7
|[[SIRT7]]
|Also situated in the cell nucleus, SIRT7 is involved in ribosome biogenesis and RNA transcription.
|Also situated in the cell nucleus, SIRT7 is involved in ribosome biogenesis and RNA transcription.
|}
|}