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SIRT1: Difference between revisions
→Activation of SIRT1
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By deacetylating nuclear factor-kappa B (NF-κB), a key regulator of inflammatory responses, SIRT1 modulates inflammation within cells, reducing the likelihood of chronic inflammation, a known contributor to aging and age-related diseases. | By deacetylating nuclear factor-kappa B (NF-κB), a key regulator of inflammatory responses, SIRT1 modulates inflammation within cells, reducing the likelihood of chronic inflammation, a known contributor to aging and age-related diseases. | ||
== Activation of SIRT1 == | |||
The activation of SIRT1 has been a focal point of research due to its potential to extend lifespan and alleviate age-related diseases. Several endogenous and exogenous factors and compounds have been identified to enhance the activity of SIRT1, impacting aging and metabolic health. | The activation of SIRT1 has been a focal point of research due to its potential to extend lifespan and alleviate age-related diseases. Several endogenous and exogenous factors and compounds have been identified to enhance the activity of SIRT1, impacting aging and metabolic health. | ||