2,851
edits
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! Notes | ! Notes | ||
|- | |- | ||
| | | [[Nicotinamide Mononucleotide (NMN)]] | ||
| NAD+ Precursor | | NAD+ Precursor | ||
| High | | High | ||
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| Converted to NMN in the body before participating in NAD+ synthesis | | Converted to NMN in the body before participating in NAD+ synthesis | ||
|- | |- | ||
| Nicotinamide (NAM) | | [[Nicotinamide (NAM)]] | ||
| NAD+ Precursor via the salvage pathway | | NAD+ Precursor via the salvage pathway | ||
| Medium | | Medium | ||
| More research needed on optimal dosing and long-term effects | | More research needed on optimal dosing and long-term effects | ||
|- | |- | ||
| Resveratrol | | [[Resveratrol]] | ||
| Sirtuin activator; may have indirect effects on NAD+ levels and metabolism | | Sirtuin activator; may have indirect effects on NAD+ levels and metabolism | ||
| Low to Medium | | Low to Medium | ||
| Effectiveness may be influenced by individual metabolic differences and supplement formulation | | Effectiveness may be influenced by individual metabolic differences and supplement formulation | ||
|- | |- | ||
| Quercetin | | [[Quercetin]] | ||
| Inhibits CD38; may increase NAD+ levels indirectly | | Inhibits CD38; may increase NAD+ levels indirectly | ||
| Low to Medium | | Low to Medium | ||
| More research needed to quantify the impact on NAD+ levels | | More research needed to quantify the impact on NAD+ levels | ||
|- | |- | ||
| Pterostilbene | | [[Pterostilbene]] | ||
| Similar to resveratrol; purported to have beneficial effects on NAD+ metabolism and sirtuin activation | | Similar to resveratrol; purported to have beneficial effects on NAD+ metabolism and sirtuin activation | ||
| Low to Medium | | Low to Medium | ||
| Requires more rigorous studies to confirm efficacy | | Requires more rigorous studies to confirm efficacy | ||
|- | |- | ||
| Exercise | | [[Exercise]] | ||
| Increases NAD+ levels likely due to enhanced energy metabolism and increased demand for ATP | | Increases NAD+ levels likely due to enhanced energy metabolism and increased demand for ATP | ||
| Medium to High | | Medium to High | ||
| Effectiveness may depend on exercise type, intensity, and individual fitness level | | Effectiveness may depend on exercise type, intensity, and individual fitness level | ||
|- | |- | ||
| Caloric Restriction | | [[Caloric Restriction]] | ||
| Elevates NAD+ levels potentially through the activation of sirtuins and improved metabolic efficiency | | Elevates NAD+ levels potentially through the activation of sirtuins and improved metabolic efficiency | ||
| High | | High | ||
| Sustained caloric restriction may have compliance challenges | | Sustained caloric restriction may have compliance challenges | ||
|- | |- | ||
| Intermittent Fasting | | [[Intermittent Fasting]] | ||
| Elevates NAD+ levels through mechanisms similar to caloric restriction | | Elevates NAD+ levels through mechanisms similar to caloric restriction | ||
| Medium to High | | Medium to High |