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After consumption, 77-80% of resveratrol gets absorbed into the bloodstream through active transport via the intestinal epithelial cells. Once in the bloodstream, it associates with albumin and lipoproteins. Despite its efficient absorption, resveratrol possesses a short half-life of around 1.5 hours. This is attributed to its rapid absorption in the intestine and subsequent degradation in the liver. A significant amount of ingested resveratrol, approximately 49–61%, is eventually excreted through urine. | After consumption, 77-80% of resveratrol gets absorbed into the bloodstream through active transport via the intestinal epithelial cells. Once in the bloodstream, it associates with albumin and lipoproteins. Despite its efficient absorption, resveratrol possesses a short half-life of around 1.5 hours. This is attributed to its rapid absorption in the intestine and subsequent degradation in the liver. A significant amount of ingested resveratrol, approximately 49–61%, is eventually excreted through urine. | ||
{| class="wikitable mw-collapsible mw-collapsed" | {| class="wikitable mw-collapsible mw-collapsed" style="width: 100%;" | ||
|+Reported resveratrol plasma concentration in humans after repeated doses of resveratrol (studies after 2010). <ref>https://www.mdpi.com/2072-6643/11/1/143</ref> | |+Reported resveratrol plasma concentration in humans after repeated doses of resveratrol (studies after 2010). <ref>https://www.mdpi.com/2072-6643/11/1/143</ref> | ||
!'''Number of Participants, Characteristics, Study Type''' | !'''Number of Participants, Characteristics, Study Type''' | ||
!'''Dose''' | !'''Dose'''<br>'''(mg/day)''' | ||
'''(mg/day)''' | |||
!'''Days''' | !'''Days''' | ||
!'''Administration''' | !'''Administration''' | ||
!'''Peak Plasma Concentration''' | !'''Peak Plasma Concentration'''<br>'''(ng/mL)''' | ||
'''(ng/mL)''' | |||
|- | |- | ||
|6, low BMI | |6, low BMI |