Translations:Resveratrol/41/de
Mehrere Faktoren führen zu Unterschieden, wie Individuen auf die Aufnahme von Resveratrol reagieren: [1]
- Zusammensetzung der Darmmikrobiota: Die einzigartige Mischung von Mikroorganismen im Darm eines Menschen.
- Genetische Unterschiede: Variationen in Genen, die Metabolismusenzyme (wie UGTs und SULTs) und Transporter beeinflussen.
- Ethnizität & Geographie: Menschen verschiedener ethnischer Herkunft oder geografischer Lage können Resveratrol unterschiedlich metabolisieren.
- Lebensstil & Ernährung: Persönliche Gewohnheiten und Ernährungsentscheidungen können die Verarbeitung von Resveratrol beeinflussen.
- Natürliche Variation: Menschen variieren natürlich, was zu unterschiedlichen Reaktionen auf Resveratrol führt.
- ↑ Springer M & Moco S: Resveratrol and Its Human Metabolites-Effects on Metabolic Health and Obesity. Nutrients 2019. (PMID 30641865) [PubMed] [DOI] [Full text] Resveratrol is one of the most widely studied polyphenols and it has been assigned a plethora of metabolic effects with potential health benefits. Given its low bioavailability and extensive metabolism, clinical studies using resveratrol have not always replicated in vitro observations. In this review, we discuss human metabolism and biotransformation of resveratrol, and reported molecular mechanisms of action, within the context of metabolic health and obesity. Resveratrol has been described as mimicking caloric restriction, leading to improved exercise performance and insulin sensitivity (increasing energy expenditure), as well as having a body fat-lowering effect by inhibiting adipogenesis, and increasing lipid mobilization in adipose tissue. These multi-organ effects place resveratrol as an anti-obesity bioactive of potential therapeutic use.