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Creatine supplementation, particularly when combined with resistance training, produces the vast majority of musculoskeletal and performance benefits in older adults. Even without exercise, creatine supplementation alone can provide some muscle and performance benefits for older adults. The supplementation has shown to be beneficial for a variety of athletic and sporting activities and provides a variety of benefits for females across their lifespan. It's also established that other forms of creatine are not superior to creatine monohydrate{{#pmid:33557850|pmid33557850}}. | Creatine supplementation, particularly when combined with resistance training, produces the vast majority of musculoskeletal and performance benefits in older adults. Even without exercise, creatine supplementation alone can provide some muscle and performance benefits for older adults. The supplementation has shown to be beneficial for a variety of athletic and sporting activities and provides a variety of benefits for females across their lifespan. It's also established that other forms of creatine are not superior to creatine monohydrate{{#pmid:33557850|pmid33557850}}. | ||
===Timing of | ===Timing of Supplementation=== | ||
A meta-study conducted in 2021, followed by another in 2022, reviewed the timing of creatine Supplementation around exercise and highlighted that the evidence supporting a specific timing (i.e., pre- versus post- versus during-exercise) remains limited and somewhat contradictory. The discrepancies in the existing data likely stem from differing supplementation protocols, sample populations, and training regimens across studies. Currently, adapting creatine timing specifically according to when training is performed is not backed by solid evidence and should not be a major concern. Both meta-studies emphasize the need for more well-controlled studies to determine whether the timing of creatine supplementation around training significantly influences intramuscular creatine content and its ergogenic effects. {{#pmid:34445003|pmid34445003}}{{#pmid:35669557|pmid35669557}} | A meta-study conducted in 2021, followed by another in 2022, reviewed the timing of creatine Supplementation around exercise and highlighted that the evidence supporting a specific timing (i.e., pre- versus post- versus during-exercise) remains limited and somewhat contradictory. The discrepancies in the existing data likely stem from differing supplementation protocols, sample populations, and training regimens across studies. Currently, adapting creatine timing specifically according to when training is performed is not backed by solid evidence and should not be a major concern. Both meta-studies emphasize the need for more well-controlled studies to determine whether the timing of creatine supplementation around training significantly influences intramuscular creatine content and its ergogenic effects. {{#pmid:34445003|pmid34445003}}{{#pmid:35669557|pmid35669557}} | ||