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Creatine: Difference between revisions

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[[File:Plasma_creatine_concentration_over_time.jpg|alt=|thumb|[[Pharmacokinetic]] profile of creatine monohydrate (CrM), tri-creatine citrate (CrC), or creatine pyruvate (CrPyr) {{#pmid:17997838|pmid17997838}} ]]
[[File:Plasma_creatine_concentration_over_time.jpg|alt=|thumb|[[Pharmacokinetic]] profile of creatine monohydrate (CrM), tri-creatine citrate (CrC), or creatine pyruvate (CrPyr) {{#pmid:17997838|pmid17997838}} ]]
In {{#pmid:17997838|pmid17997838}} the effects of ingesting isomolar amounts of creatine (4.4 g) in the form of the monohydrate (5 g), tri-creatine citrate (6.7 g) and creatine pyruvate (7.3 g) on creatine concentrations in plasma was compared. The dosage per from were isomolar, meaning every form had the same amount of active molecules. Since the molar mass per form is different, that results in different doses. The findings suggest that different forms of creatine result in slightly altered kinetics of plasma creatine absorption following ingestion. Differences in bioavailability are thought to be unlikely since absorption of creatine monohydrate is already close to 100%. The small differences in kinetics are unlikely to have any effect on muscle creatine elevation during periods of creatine loading.
In {{#pmid:17997838|pmid17997838}} the effects of ingesting isomolar amounts of creatine (4.4 g) in the form of the monohydrate (5 g), tri-creatine citrate (6.7 g) and creatine pyruvate (7.3 g) on creatine concentrations in plasma was compared. The dosage per from were isomolar, meaning every form had the same amount of active molecules. Since the molar mass per form is different, that results in different doses. The findings suggest that different forms of creatine result in slightly altered kinetics of plasma creatine absorption following ingestion. Differences in bioavailability are thought to be unlikely since absorption of creatine monohydrate is already close to 100%. The small differences in kinetics are unlikely to have any effect on muscle creatine elevation during periods of creatine loading.


==Potential Benefits==
==Potential Benefits==
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