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Creatine supplementation has shown potential in managing blood sugar levels by increasing the body's ability to utilize glucose as metabolic fuel. This is particularly beneficial for diabetic individuals. Studies have shown creatine supplementation alongside moderate exercise improves oral glucose tolerance test results, indicating creatine's potential benefit in blood sugar regulation. | Creatine supplementation has shown potential in managing blood sugar levels by increasing the body's ability to utilize glucose as metabolic fuel. This is particularly beneficial for diabetic individuals. Studies have shown creatine supplementation alongside moderate exercise improves oral glucose tolerance test results, indicating creatine's potential benefit in blood sugar regulation. | ||
==Potential Therapeutic Role== | ==Potential Therapeutic Role== | ||
=== Creatine Deficiency Syndrome === | === Creatine Deficiency Syndrome === | ||
Robust evidence highlights the significance of creatine on cognitive function, particularly observed in individuals with creatine deficient syndromes known to deplete brain creatine stores. Creatine deficiency syndrome is marked by mental and developmental disorders, including learning delays and seizures. Notably, these symptoms are, to some extent, reversed by creatine supplementation. Human studies have yielded mixed results. While some studies have discovered benefits on cognitive functioning, others found no such effects, as comprehensively reviewed by Roschel and colleagues in 2022. {{#pmid:35267907|pmid35267907}} | Robust evidence highlights the significance of creatine on cognitive function, particularly observed in individuals with creatine deficient syndromes known to deplete brain creatine stores. Creatine deficiency syndrome is marked by mental and developmental disorders, including learning delays and seizures. Notably, these symptoms are, to some extent, reversed by creatine supplementation. Human studies have yielded mixed results. While some studies have discovered benefits on cognitive functioning, others found no such effects, as comprehensively reviewed by Roschel and colleagues in 2022. {{#pmid:35267907|pmid35267907}} |