Creatine: Difference between revisions

===Lifespan===

In animal studies, creatine supplementation has been associated with a 9% increase in lifespan. Creatine-fed mice also demonstrated significantly better performance on neurobehavioral testing. While human trials are needed to confirm these findings, they suggest a potential benefit of creatine supplementation for longevity.

Sarcopenia, an age-related condition, leads to reduced muscle mass, strength, and functionality. Aging also generally causes loss of muscle mass, bone mass, and balance while increasing body fat. Various interventions like creatine supplementation alongside resistance training have been proposed to counteract these issues. Some studies have shown that creatine supplementation during resistance training can significantly improve muscle mass, strength, and even bone density in older individuals. For instance, creatine has been observed to enhance muscle mass and strength in older men and postmenopausal women during resistance training, and improve balance in individuals after sleep deprivation. Creatine's effect extends to promoting muscle endurance, functional task performance, and even fat loss, which could be beneficial in managing adult-onset obesity while preserving muscle mass during weight loss interventions. These findings suggest that creatine supplementation, especially when combined with resistance training, could be a promising strategy to combat age-related muscle and bone deterioration, and help in managing adult-onset obesity. Further studies are required to solidify these findings and understand the long-term implications of creatine supplementation in older individuals.