Bioavailability: Difference between revisions

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	[[File:AUC iv po.svg\|~~mini\|upright=1.2~~\|Bioavailability after intravenous administration (by definition 100%, <span style="color:#dd0000">'''red'''</span>, i.v.) and after oral administration ('''black''', <span style="color:#909090">'''grey'''</span>, p.o.): If the areas under the curves for the period <math>{0-\infty}</math> are equal for both methods of administration, the oral bioavailability also corresponds to 100% (grey area under black curve). Smaller areas correspond to lower bioavailability. <math>c_{t}=</math> drug concentration in plasma, <math>t=</math> time.]]		[[File:AUC iv po.svg\|thumb\|Bioavailability after intravenous administration (by definition 100%, <span style="color:#dd0000">'''red'''</span>, i.v.) and after oral administration ('''black''', <span style="color:#909090">'''grey'''</span>, p.o.): If the areas under the curves for the period <math>{0-\infty}</math> are equal for both methods of administration, the oral bioavailability also corresponds to 100% (grey area under black curve). Smaller areas correspond to lower bioavailability. <math>c_{t}=</math> drug concentration in plasma, <math>t=</math> time.]]
	Bioavailability is a key concept in pharmacology and nutrition, referring to the rate and extent to which a substance is absorbed into the bloodstream and made available at the site of physiological activity. This concept is crucial for both pharmaceuticals and nutraceuticals, as it determines the effectiveness of drugs and dietary supplements.		Bioavailability is a key concept in pharmacology and nutrition, referring to the rate and extent to which a substance is absorbed into the bloodstream and made available at the site of physiological activity. This concept is crucial for both pharmaceuticals and nutraceuticals, as it determines the effectiveness of drugs and dietary supplements.