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'''Nano-based delivery systems''' refer to the utilization of nanotechnology to enhance the delivery and [[bioavailability]] of various nutrients and bioactive components. These systems are revolutionizing the way nutrients are absorbed and utilized in the body, especially in the context of food and supplements. {{pmid|34136200}} | '''Nano-based delivery systems''' refer to the utilization of nanotechnology to enhance the delivery and [[bioavailability]] of various nutrients and bioactive components. These systems are revolutionizing the way nutrients are absorbed and utilized in the body, especially in the context of food and supplements. {{pmid|34136200}} | ||
[[File:nano‐based delivery systems.jpg|frame|Different nano‐based delivery systems to improve the bioavailability of encapsulated micronutrients {{pmid|34136200}}]] | === Overview === | ||
[[File:nano‐based delivery systems.jpg|frame|Different nano‐based delivery systems to improve the bioavailability of encapsulated micronutrients. These include liposomes, micelles, reverse micelles, emulsion droplets, microemulsions, solid lipid particles, molecular complexes, biopolymers nanoparticles, hydrogel particles, filled hydrogel particles, and polyelectrolyte complexes. The delivery systems are designed to encapsulate either hydrophilic (blue) or hydrophobic (orange) bioactive compounds, enhancing stability and controlled release. {{pmid|34136200}}]] | |||
The image depicts a variety of nano-based delivery systems, each designed to improve the stability, bioavailability, and controlled release of both hydrophilic and hydrophobic bioactive compounds: | |||
* '''Liposomes''': Phospholipid bilayer vesicles that encapsulate hydrophilic compounds. | |||
* '''Micelles''': Amphiphilic molecules forming a hydrophobic core and a hydrophilic shell for hydrophobic compounds. | |||
* '''Reverse Micelles''': Structures with a hydrophilic interior and hydrophobic exterior, for hydrophilic compounds in hydrophobic media. | |||
* '''Emulsion Droplets''': Liquid droplets dispersed within another liquid, carrying both hydrophobic and hydrophilic compounds. | |||
* '''Micro Emulsions''': Thermodynamically stable mixtures that solubilize hydrophobic compounds. | |||
* '''Solid Lipid Particles''': Particles made from solid lipids for hydrophobic compounds. | |||
* '''Molecular Complex''': Interactions between a drug molecule and a carrier to improve solubility. | |||
* '''Biopolymers Nanoparticles''': Biodegradable polymer particles for drug encapsulation. | |||
* '''Hydrogel Particles''': Hydrophilic polymer networks that encapsulate hydrophilic compounds. | |||
* '''Filled Hydrogel Particles''': Hydrogel particles with a core filled with another substance. | |||
* '''Polyelectrolyte Complex''': Formed by the interaction of charged polyelectrolytes, suitable for charged molecules like DNA or proteins. | |||
These innovative systems are critical in pharmaceuticals and nutrition for enhancing therapeutic efficacy and nutritional value by improving solubility, protection from degradation, and controlled release profiles. | |||
=== Nutrient Enhancers and Inhibitors === | === Nutrient Enhancers and Inhibitors === |