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Yeast (Saccharomyces Cerevisiae): Difference between revisions
Yeast (Saccharomyces Cerevisiae) (view source)
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When researchers look for an organism to use in their studies, they look for several traits. Among these are size, generation time, accessibility, manipulation, genetics, conservation of mechanisms, and potential economic benefit. The yeast species ''S. pombe'' and ''S. cerevisiae'' are both well studied; these two species diverged approximately 600 to 300 million years ago, and are significant tools in the study of DNA damage and repair mechanisms.<ref>{{cite book |first1= Jac A. |last1=Nickoloff |first2=James E. |last2=Haber |date=2011 |chapter=Mating-Type Control of DNA Repair and Recombination in ''Saccharomyces cerevisiae'' |doi=10.1007/978-1-59259-095-7_5 |pages=107–124 |editor1-first=Jac A. |editor1-last=Nickoloff |editor2-first=Merl F. |editor2-last=Hoekstra |title=DNA Damage and Repair |series=Contemporary Cancer Research |isbn=978-1-59259-095-7|doi-broken-date=1 August 2023 | chapter-url=https://link.springer.com/chapter/10.1007/978-1-59259-095-7_5}}</ref> | When researchers look for an organism to use in their studies, they look for several traits. Among these are size, generation time, accessibility, manipulation, genetics, conservation of mechanisms, and potential economic benefit. The yeast species ''S. pombe'' and ''S. cerevisiae'' are both well studied; these two species diverged approximately 600 to 300 million years ago, and are significant tools in the study of DNA damage and repair mechanisms.<ref>{{cite book |first1= Jac A. |last1=Nickoloff |first2=James E. |last2=Haber |date=2011 |chapter=Mating-Type Control of DNA Repair and Recombination in ''Saccharomyces cerevisiae'' |doi=10.1007/978-1-59259-095-7_5 |pages=107–124 |editor1-first=Jac A. |editor1-last=Nickoloff |editor2-first=Merl F. |editor2-last=Hoekstra |title=DNA Damage and Repair |series=Contemporary Cancer Research |isbn=978-1-59259-095-7|doi-broken-date=1 August 2023 | chapter-url=https://link.springer.com/chapter/10.1007/978-1-59259-095-7_5}}</ref> | ||
''S. cerevisiae'' has developed as a [[model organism]] because it scores favorably on a number of these criteria. | ''S. cerevisiae'' has developed as a [[Model Organism|model organism]] because it scores favorably on a number of these criteria. | ||
* As a single-cell organism, ''S. cerevisiae'' is small with a short generation time (doubling time 1.25–2 hours<ref>{{cite book |editor=Boekhout, T. |editor2=Robert, V. |date=2003 |title=Yeasts in Food: Beneficial and Detrimental aspects |publisher=Behr's Verlag |isbn=978-3-86022-961-3 |page=322 |url=https://books.google.com/books?id=GG-60Vtl81EC |access-date=January 10, 2011}}</ref> at {{convert|30|C|F|disp=or}}) and can be easily cultured. These are all positive characteristics in that they allow for the swift production and maintenance of multiple specimen lines at low cost. | * As a single-cell organism, ''S. cerevisiae'' is small with a short generation time (doubling time 1.25–2 hours<ref>{{cite book |editor=Boekhout, T. |editor2=Robert, V. |date=2003 |title=Yeasts in Food: Beneficial and Detrimental aspects |publisher=Behr's Verlag |isbn=978-3-86022-961-3 |page=322 |url=https://books.google.com/books?id=GG-60Vtl81EC |access-date=January 10, 2011}}</ref> at {{convert|30|C|F|disp=or}}) and can be easily cultured. These are all positive characteristics in that they allow for the swift production and maintenance of multiple specimen lines at low cost. | ||
* ''S. cerevisiae'' divides with meiosis, allowing it to be a candidate for sexual genetics research. | * ''S. cerevisiae'' divides with meiosis, allowing it to be a candidate for sexual genetics research. | ||