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Domestic Dogs (Canis Familiaris): Difference between revisions
Domestic Dogs (Canis Familiaris) (view source)
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==Reasons for Choosing Dogs== | ==Reasons for Choosing Dogs== | ||
Dogs share many environmental exposures with humans and exhibit a wide range of lifespans and physiological traits. This diversity provides a unique opportunity to study the genetic and environmental factors affecting longevity. | Dogs share many environmental exposures with humans and exhibit a wide range of lifespans and physiological traits. This diversity provides a unique opportunity to study the genetic and environmental factors affecting longevity. Additionally, their close living proximity with humans allows for the assessment of environmental influences on morbidity and mortality in both species. | ||
==Comparative Biology of Aging in Dogs== | ==Comparative Biology of Aging in Dogs== | ||
[[File:Survivorship and hazard curves for for human and dogs.jpg|thumb|alt=|Survivorship (a) and hazard curves for (b) for human (left) and dogs (right). Human data are from the U.S. Census Bureau (1972–2002), and canine data come from the VetCompass database (2010–2013). For both species, colors represent the two sexes, female (red) and male (blue). {{pmid|29457329}}]] | [[File:Survivorship and hazard curves for for human and dogs.jpg|thumb|alt=|Survivorship (a) and hazard curves for (b) for human (left) and dogs (right). Human data are from the U.S. Census Bureau (1972–2002), and canine data come from the VetCompass database (2010–2013). For both species, colors represent the two sexes, female (red) and male (blue). {{pmid|29457329}}]] | ||
The biology of aging in dogs varies significantly across breeds, offering insights into how genetic diversity influences aging. Studies on canine aging also help in understanding age-related diseases and their progression. | The biology of aging in dogs varies significantly across breeds, offering insights into how genetic diversity influences aging. Studies on canine aging also help in understanding age-related diseases and their progression. Comparative analyses of morbidity and mortality between humans and dogs have shown significant similarities in the effects of age on disease risk, especially in neoplastic, congenital, and metabolic causes of death. | ||
==Genetic Factors in Canine Longevity== | ==Genetic Factors in Canine Longevity== | ||
Research into the canine genome has identified various genetic factors that contribute to their longevity. These findings are crucial for understanding the genetic basis of aging and developing interventions to extend healthy lifespan. | Research into the canine genome has identified various genetic factors that contribute to their longevity. These findings are crucial for understanding the genetic basis of aging and developing interventions to extend healthy lifespan. The history of intense breeding in dogs for specific traits has resulted in a species with considerable genetic variation among breeds, which is valuable for studying genetic influences on longevity and disease. | ||
==Environmental and Lifestyle Factors== | ==Environmental and Lifestyle Factors== | ||
Factors such as diet, exercise, and living conditions play a significant role in the longevity of dogs. These aspects offer valuable insights into how lifestyle choices impact aging and healthspan. | Factors such as diet, exercise, and living conditions play a significant role in the longevity of dogs. These aspects offer valuable insights into how lifestyle choices impact aging and healthspan. Dogs' exposure to diverse environments, often mirroring those of humans, makes them ideal for studying the impact of environment on aging. | ||
==Human-Canine Health Comparisons== | |||
A large-scale comparison of human and canine patterns of morbidity and mortality has revealed that many chronic conditions common in humans, such as obesity, arthritis, and diabetes, are also prevalent in dogs. This similarity extends to the association with comorbidities, suggesting that dogs can be a powerful model for studying human health issues. However, there are differences in certain areas, such as cardiovascular disease, highlighting the need for detailed comparative studies. | |||
== See Also == | == See Also == | ||