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== Rationale for Use ==
== Rationale for Use ==
=== Physiological Similarity to Humans ===
* '''Physiological Similarity to Humans:''' NHPs are crucial for understanding human biology and medicine, especially in areas like brain function and infectious disease prevention. Their close genetic and physiological similarities to humans, including similar organ systems, immune responses, and brain structures, make them valuable models for human health studies.
NHPs are crucial for understanding human biology and medicine, especially in areas like brain function and infectious disease prevention.
* '''Drug Testing and Vaccine Development:''' NHPs play a vital role in the safety testing of new drugs and in the development of vaccines. Their similarity to humans in terms of metabolism, pharmacokinetics, and pharmacodynamics is essential for assessing the efficacy and safety of new medical treatments before they are tested in human trials.
 
* '''Neurological Research:''' NHPs are especially important in neurological research due to their complex brain structures that closely resemble those of humans. They are used in studies of neurodegenerative diseases, cognitive function, and brain disorders, providing insights that are not possible with other model organisms.
=== Drug Testing and Vaccine Development ===
* '''Infectious Disease Research:''' Given their similar immune system responses, NHPs are indispensable in the study of infectious diseases, including HIV/AIDS, Zika virus, and other emerging pathogens. They help in understanding disease progression and in testing the effectiveness of antiviral drugs and vaccines.
NHPs play a vital role in the safety testing of new drugs and in the development of vaccines due to their close resemblance to human organ systems and immune responses.
* '''Translational Research:''' NHPs serve as a critical bridge in translational research, which aims to apply findings from basic science to enhance human health and disease treatments. Their use often leads to direct applications in clinical settings, improving the development of diagnostic methods, treatments, and preventive strategies for various diseases.
* '''Ethical Implications:''' While NHPs provide invaluable insights in biomedical research, their use also raises ethical questions due to their cognitive abilities and social structures. This necessitates strict regulations and ethical oversight to ensure their welfare in research settings.


== Global Usage and Statistics ==
== Global Usage and Statistics ==
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