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NADase: Difference between revisions
→Known NADase Enzymes
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|'''[[PARP2]]'''||Similar to PARP1, PARP2 is involved in DNA repair. It also helps maintain genomic stability and regulates gene expression.||DNA repair, genomic stability, gene expression regulation.||Located in the cell nucleus, expressed in a range of cell types.||Influences DNA maintenance and repair processes important in aging.||Cancers, particularly those sensitive to DNA damage, some genetic disorders. | |'''[[PARP2]]'''||Similar to PARP1, PARP2 is involved in DNA repair. It also helps maintain genomic stability and regulates gene expression.||DNA repair, genomic stability, gene expression regulation.||Located in the cell nucleus, expressed in a range of cell types.||Influences DNA maintenance and repair processes important in aging.||Cancers, particularly those sensitive to DNA damage, some genetic disorders. | ||
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|'''[[Sirtuins (SIRT1-SIRT7)]]'''||Sirtuins, a family of NAD+-dependent enzymes (SIRT1-SIRT7), are involved in a wide range of cellular processes. Each sirtuin has distinct functions, from DNA repair to metabolic regulation.||Gene expression regulation, DNA repair, metabolism, stress resistance, cell survival.||Diverse expression patterns; SIRT1, SIRT3, and SIRT6 are key in metabolic regulation.||Critical in cellular aging, metabolic health, and stress responses.||Aging, metabolic disorders, cardiovascular diseases, neurodegenerative diseases. | |'''[[Sirtuins|Sirtuins (SIRT1-SIRT7)]]'''||Sirtuins, a family of NAD+-dependent enzymes (SIRT1-SIRT7), are involved in a wide range of cellular processes. Each sirtuin has distinct functions, from DNA repair to metabolic regulation.||Gene expression regulation, DNA repair, metabolism, stress resistance, cell survival.||Diverse expression patterns; SIRT1, SIRT3, and SIRT6 are key in metabolic regulation.||Critical in cellular aging, metabolic health, and stress responses.||Aging, metabolic disorders, cardiovascular diseases, neurodegenerative diseases. | ||
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