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Coenzyme Q10 (CoQ10): Difference between revisions
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As the only endogenous lipid antioxidant, CoQ<sub>10</sub> is critical in neutralizing free radicals, thus protecting against DNA damage and cellular dysfunction that are symptomatic of aging. By preserving cellular integrity, CoQ<sub>10</sub>'s antioxidant action is proposed to impede aging and potentially extend cellular lifespan. | As the only endogenous lipid antioxidant, CoQ<sub>10</sub> is critical in neutralizing free radicals, thus protecting against DNA damage and cellular dysfunction that are symptomatic of aging. By preserving cellular integrity, CoQ<sub>10</sub>'s antioxidant action is proposed to impede aging and potentially extend cellular lifespan. | ||
It also contributes to the regulation of mitochondrial function, such as influencing uncoupling proteins and the mitochondrial permeability transition pore, which are crucial for cell survival and apoptosis, respectively. Such regulation is particularly important as mitochondrial dysfunction is a noted characteristic of aging {{pmid|35199552}}. | It also contributes to the regulation of mitochondrial function, such as influencing uncoupling proteins and the mitochondrial permeability transition pore, which are crucial for cell survival and [[Apoptosis|apoptosis]], respectively. Such regulation is particularly important as mitochondrial dysfunction is a noted characteristic of aging {{pmid|35199552}}. | ||
== Potential Therapeutic Role == | == Potential Therapeutic Role == | ||