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Insulin/IGF-1 Signaling (IIS) Pathway: Difference between revisions
Insulin/IGF-1 Signaling (IIS) Pathway (view source)
Revision as of 01:37, 15 January 2024
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The '''Insulin/IGF-1 Signaling (IIS) pathway''' is a significant biochemical pathway that has been extensively studied in the context of aging and longevity. This pathway, conserved across various species, plays a critical role in regulating lifespan, stress resistance, and metabolism. | The '''Insulin/IGF-1 Signaling (IIS) pathway''' is a significant biochemical pathway that has been extensively studied in the context of aging and longevity. This pathway, conserved across various species, plays a critical role in regulating lifespan, stress resistance, and metabolism. | ||
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== Mechanism == | == Mechanism == | ||
The pathway involves several key components: | The pathway involves several key components: | ||
* '''Insulin and IGF-1 Receptors:''' These receptors, upon activation by insulin or IGF-1, initiate the signaling cascade. | * '''Insulin and IGF-1 Receptors:''' These receptors, upon activation by insulin or IGF-1, initiate the signaling cascade. | ||