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| == Antioxidative Stress == | | == Antioxidative Stress == |
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| | '''Antioxidative stress''' is the fundamental opposite is oxidative stress. It is an overabundance of [[Bioavailability|bioavailable]] [[Antioxidant|antioxidant]] compounds that interfere with the immune system's ability to neutralize pathogenic threats. |
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| The fundamental opposite is [[Oxidative stress|oxidative stress]]
| | Antioxidant compounds reduce reactive oxygen species (ROS), which reduces emitted free-radicals. When ROS function is impaired, there is more susceptibility to [[Atopy|atopic]] disorders or diseases due to impairment of the attack-kill-present-respond behavior of the Th-1 immune response chain. Over-consumption of antioxidants could thus lead to antioxidative stress, where antioxidants might weaken or block the adaptive stress responses and cause dangerous health conditions and cause harm.<ref name=":0">{{Cite journal|title=The Neglected Significance of "Antioxidative Stress"|journal=Oxidative Medicine and Cellular Longevity|volume=2012|pages=480895|date=Feb 17, 2012|doi=10.1155/2012/480895|pmid=22655114|pmc=3357598|last1=Poljsak|first1=B.|last2=Milisav|first2=I.|doi-access=free}}</ref> |
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| '''Antioxidative stress''' is an overabundance of [[Bioavailability|bioavailable]] [[Antioxidant|antioxidant]] compounds that interfere with the [[Immune system|immune system]]'s ability to neutralize pathogenic threats. The fundamental opposite is [[Oxidative stress|oxidative stress]], which can lead to such disease states as coronary heart disease or cancer.<ref>{{Cite journal|last1=Valko|date=2006-03-10|issn=0009-2797|doi=10.1016/j.cbi.2005.12.009|pages=1–40|issue=1|volume=160|journal=Chemico-Biological Interactions|title=Free radicals, metals and antioxidants in oxidative stress-induced cancer|first5=M.|first1=M.|last5=Mazur|first4=M.|last4=Izakovic|first3=J.|last3=Moncol|first2=C. J.|last2=Rhodes|pmid=16430879}}</ref>
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| Antioxidant compounds reduce [[Reactive oxygen species|reactive oxygen species]] (ROS), which reduces emitted [[Free radical|free-radicals]]. When ROS function is impaired, there is more susceptibility to [[Atopy|atopic]] disorders or diseases due to impairment of the attack-kill-present-respond behavior of the [[T helper cell|Th-1 immune response chain]]. Over-consumption of antioxidants could thus lead to antioxidative stress, where antioxidants might weaken or block the adaptive stress responses and cause dangerous health conditions and cause harm.<ref name=":0">{{Cite journal|title=The Neglected Significance of "Antioxidative Stress"|journal=Oxidative Medicine and Cellular Longevity|volume=2012|pages=480895|date=Feb 17, 2012|doi=10.1155/2012/480895|pmid=22655114|pmc=3357598|last1=Poljsak|first1=B.|last2=Milisav|first2=I.|doi-access=free}}</ref> | |
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| == Health effects == | | == Health effects == |
