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| colspan="1" rowspan="1" |1985 | | colspan="1" rowspan="1" |1985 | ||
| colspan="1" rowspan="1" |PCA uses fewer uncorrelated variables to explain the main variance | | colspan="1" rowspan="1" |PCA uses fewer uncorrelated variables to explain the main variance | ||
| colspan="1" rowspan="1" | | | colspan="1" rowspan="1" | | ||
# Biomarkers are uncorrelated variables{{pmid|16318865}} | |||
# PCA avoids the influence of regression edge in MLR{{pmid|3226152}} | |||
| colspan="1" rowspan="1" |PCA cannot avoid the paradox of CA and some statistical deficiencies of MLR{{pmid|16318865}} | | colspan="1" rowspan="1" |PCA cannot avoid the paradox of CA and some statistical deficiencies of MLR{{pmid|16318865}} | ||
| colspan="1" rowspan="1" |Nakamura et al,{{pmid|2737197}}{{pmid|2282902}} Nakamura and Miyao,{{pmid|12634284}} Nakamura et al,{{pmid|8026568}}{{pmid|9762521}} Nakamura and Miyao,{{pmid|17921421}} Nakamura et al,{{pmid|3226152}} Nakamura,<ref>75. Nakamura E. The assessment of physiological age based upon a principal component analysis of various physiological variables. J Kyoto Pref Univ Med. 1985;94:757–769. [Google Scholar]</ref> Nakamura and Miyao,{{pmid|18840798}} Nakamura et al,{{pmid|8803500}} Park et al,{{pmid|18597867}} Bai et al,{{pmid|19940465}} and Zhang{{pmid|25470806}}–{{pmid|24659482}} | | colspan="1" rowspan="1" |Nakamura et al,{{pmid|2737197}}{{pmid|2282902}} Nakamura and Miyao,{{pmid|12634284}} Nakamura et al,{{pmid|8026568}}{{pmid|9762521}} Nakamura and Miyao,{{pmid|17921421}} Nakamura et al,{{pmid|3226152}} Nakamura,<ref>75. Nakamura E. The assessment of physiological age based upon a principal component analysis of various physiological variables. J Kyoto Pref Univ Med. 1985;94:757–769. [Google Scholar]</ref> Nakamura and Miyao,{{pmid|18840798}} Nakamura et al,{{pmid|8803500}} Park et al,{{pmid|18597867}} Bai et al,{{pmid|19940465}} and Zhang{{pmid|25470806}}–{{pmid|24659482}} |