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Trimethylglycine (TMG): Difference between revisions

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'''Trimethylglycine''' is an amino acid derivative that occurs in plants. Trimethylglycine was the first betaine discovered; originally it was simply called '''betaine''' because, in the 19th century, it was discovered in sugar beets (''Beta vulgaris'' subsp. ''vulgaris'').
Trimethylglycine, commonly known as TMG or betaine, is an amino acid derivative that naturally occurs in various plant and animal sources. With its three methyl groups attached to a glycine molecule, TMG has garnered attention in both the dietary supplement market and the scientific community due to its role as a methyl donor in vital biochemical processes.


Although trimethylglycine supplementation decreases the amount of [[wikipedia:Adipose_tissue|adipose tissue]] in pigs, research on human subjects has shown no effect on body weight, body composition, or resting energy expenditure when used in conjunction with a low calorie diet.<ref name="pmid12399266">{{cite journal|last1=Schwab|volume=76|doi-access=free|doi=10.1093/ajcn/76.5.961|pmid=12399266|date=November 2002|pages=961–967|issue=5|journal=Am. J. Clin. Nutr.|first1=U.|title=Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects|display-authors=etal|first3=L.|last3=Toppinen|first2=A.|last2=Törrönen|title-link=doi}}</ref>
Although trimethylglycine supplementation decreases the amount of [[wikipedia:Adipose_tissue|adipose tissue]] in pigs, research on human subjects has shown no effect on body weight, body composition, or resting energy expenditure when used in conjunction with a low calorie diet.<ref name="pmid12399266">{{cite journal|last1=Schwab|volume=76|doi-access=free|doi=10.1093/ajcn/76.5.961|pmid=12399266|date=November 2002|pages=961–967|issue=5|journal=Am. J. Clin. Nutr.|first1=U.|title=Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects|display-authors=etal|first3=L.|last3=Toppinen|first2=A.|last2=Törrönen|title-link=doi}}</ref>
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