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!Description | !Description | ||
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|SIRT1 | |[[SIRT1]] | ||
|Found primarily in the cell nucleus, SIRT1 is involved in DNA repair, gene expression regulation, and various metabolic processes. | |Found primarily in the cell nucleus, SIRT1 is involved in DNA repair, gene expression regulation, and various metabolic processes. | ||
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|SIRT2 | |[[SIRT2]] | ||
|Predominantly found in the cytoplasm, SIRT2 regulates cell cycle progression and is associated with maintaining cell integrity. | |Predominantly found in the cytoplasm, SIRT2 regulates cell cycle progression and is associated with maintaining cell integrity. | ||
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|SIRT3, SIRT4 and SIRT5 | |[[SIRT3]], [[SIRT4]] and [[SIRT5]] | ||
|These sirtuins are primarily located in the mitochondria and are pivotal for maintaining mitochondrial function, energy production, and metabolic homeostasis. | |These sirtuins are primarily located in the mitochondria and are pivotal for maintaining mitochondrial function, energy production, and metabolic homeostasis. | ||
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|SIRT6 | |[[SIRT6]] | ||
|Operating within the cell nucleus, SIRT6 plays a crucial role in DNA repair, genome stability, and metabolic regulation. | |Operating within the cell nucleus, SIRT6 plays a crucial role in DNA repair, genome stability, and metabolic regulation. | ||
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|SIRT7 | |[[SIRT7]] | ||
|Also situated in the cell nucleus, SIRT7 is involved in ribosome biogenesis and RNA transcription. | |Also situated in the cell nucleus, SIRT7 is involved in ribosome biogenesis and RNA transcription. | ||
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