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Quercetin: Difference between revisions
→Quercetin Phytosome
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===Quercetin Phytosome=== | ===Quercetin Phytosome=== | ||
[[File:Pharmacokinetic profile of quercetin.png|thumb|Pharmacokinetic profile of standard quercetin and quercetin phytosome in the clinical study. The plasma concentrations of quercetin obtained after single oral administration of the unformulated quercetin at 500 mg/tablet and after single oral administration of its corresponding lecithin formulation, Quercetin Phytosome, at a dose of either 500 or 250 mg are shown. <ref name=":0">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418071/</ref>]] | [[File:Pharmacokinetic profile of quercetin.png|thumb|Pharmacokinetic profile of standard quercetin and quercetin phytosome in the clinical study. The plasma concentrations of quercetin obtained after single oral administration of the unformulated quercetin at 500 mg/tablet and after single oral administration of its corresponding lecithin formulation, Quercetin Phytosome, at a dose of either 500 or 250 mg are shown. <ref name=":0">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418071/</ref>]] | ||
Quercetin Phytosome is a formulation where quercetin is bound to phospholipids, typically derived from sunflower or soy lecithin, to enhance its bioavailability and absorption. The relevant clinical study used Quercetin Phytosome (QUERCEFIT™) consisting of quercetin and sunflower lecithin in a 1:1 weight ratio along with about a fifth part of food-grade excipients that are added to improve the physical state of the product and to standardize it to an HPLC-measured total quercetin content of about 40%. | Quercetin Phytosome is a formulation where quercetin is bound to phospholipids, typically derived from sunflower or soy lecithin, to enhance its bioavailability and absorption. The relevant clinical study used Quercetin Phytosome (QUERCEFIT™) consisting of quercetin and sunflower lecithin in a 1:1 weight ratio along with about a fifth part of food-grade excipients that are added to improve the physical state of the product and to standardize it to an HPLC-measured total quercetin content of about 40%. In the clinical study, a ~20-fold increase in bioavailability was measured compared to standard quercetin with equal doses. <ref name=":0" /> | ||
In the clinical study, a ~20-fold increase in bioavailability was measured compared to standard quercetin with equal doses. | |||
{| class="wikitable" | {| class="wikitable" | ||
|+Pharmacokinetic parameters <ref name=":0" /> | |+Pharmacokinetic parameters <ref name=":0" /> | ||