Area Under the Curve (AUC): Difference between revisions

Area Under the Curve (AUC) (view source)

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 AUC offers insight into the extent and rate of drug absorption, making it a fundamental measure to assess bioavailability and bioequivalence of drugs.
-===Types of AUC===
-Several types of AUC values exist, each serving unique purposes in pharmacokinetic studies:
-*'''<math>\text{AUC}_{\text{last}}</math>''': Represents the AUC from the time of administration up to the last measurable concentration.
-*'''<math>\text{AUC}_{0\to\infty}</math>''': Represents the total AUC from the time of administration extrapolated to infinity.
-*'''<math>\text{AUC}_{0\to t}</math>''': Represents the AUC from the time of administration up to a specific time 't'.
-*'''<math>\text{AUC}_{\tau}</math>''': Represents the AUC over a dosing interval 'tau'.
-===Application===
-AUC is indispensable in pharmacology and drug development:
-*It is pivotal for determining the dosage and frequency of drug administration.
-*It aids in evaluating the bioequivalence of generic drugs to brand-name counterparts.
-*It enables researchers to study the pharmacokinetics of new drug candidates.
-===See Also===
-*Pharmacokinetics
-*Drug Metabolism
-*Bioavailability
-*Bioequivalence
-==References==
-<!-- Include references here -->
 ==Types of AUC==
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 |Suitable for studying the pharmacokinetics of drugs at subtherapeutic, micro-level doses.
 |}
+===Application===
+AUC is indispensable in pharmacology and drug development:
+*It is pivotal for determining the dosage and frequency of drug administration.
+*It aids in evaluating the bioequivalence of generic drugs to brand-name counterparts.
+*It enables researchers to study the pharmacokinetics of new drug candidates.
+===See Also===
+*Pharmacokinetics
+*Drug Metabolism
+*Bioavailability
+*Bioequivalence