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Resveratrol: Difference between revisions

51 bytes removed ,  14 October 2023
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===Resveratrol with Piperine===
===Resveratrol with Piperine===
In 2021 a double-blind, randomized, three arm pilot study was performed. Participants were randomized to receive a single dose of resveratrol 2500 mg, with piperine in 0 mg, 5 mg or 25 mg dose. Despite the observation of piperine coadministration significantly increasing bioavailability ([[Cmax|C<sub>max</sub>]] and [[AUC|AUC)]] of resveratrol in [[C57BL/6 mice|C57BL]] mice, no significant increase in resveratrol or decrease in resveratrol glucuronide could be observed in healthy adults taking 2500 gm of resveratrol with piperine (5 or 25 mg) as compared to resveratrol alone. <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910313/</ref>
In 2021 [[Randomized Controlled Trial]], participants receive a single dose of resveratrol 2500 mg, with piperine in 0 mg, 5 mg or 25 mg dose. Despite the observation of piperine coadministration significantly increasing bioavailability ([[Cmax|C<sub>max</sub>]] and [[AUC|AUC)]] of resveratrol in [[C57BL/6 mice|C57BL]] mice, no significant increase in resveratrol or decrease in resveratrol glucuronide could be observed in healthy adults taking 2500 gm of resveratrol with piperine (5 or 25 mg) as compared to resveratrol alone. <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910313/</ref>


===Micronized Resveratrol ===
===Micronized Resveratrol ===
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