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Hallmarks of Aging: Difference between revisions

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Hallmarks of Aging (view source)

Revision as of 17:00, 1 January 2024

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→‎The 14 Hallmarks of Aging (2023)
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! Hallmark
! Hallmark
! Description
! Description
!
!Category
!Level
|-
|-
| '''Genomic instability'''
| '''Genomic instability'''
| Accumulation of DNA damage over time leading to cellular dysfunction.
| Accumulation of DNA damage over time leading to cellular dysfunction.
| rowspan="6" |'''Primary Hallmarks'''
| rowspan="5" |'''Primary Hallmarks'''
(causes damage)
(causes damage)
| rowspan="6" |Molecular
|-
|-
| '''Telomere attrition'''
| '''Telomere attrition'''
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|'''Compromised autophagy'''
|'''Compromised autophagy'''
|Impaired cellular maintenance through the consumption of own components.
|Impaired cellular maintenance through the consumption of own components.
| rowspan="4" |'''Antagonistic Hallmarks'''
(responses to damage)
|-
|-
|'''Deregulated nutrient sensing'''
|'''Deregulated nutrient sensing'''
| Alterations in nutrient sensing pathways affecting metabolism and aging.
| Alterations in nutrient sensing pathways affecting metabolism and aging.
| rowspan="3" |'''Antagonistic Hallmarks'''
| rowspan="8" |Cellular & Organismal
(responses to damage)
|-
|-
|'''Mitochondrial dysfunction'''
|'''Mitochondrial dysfunction'''
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