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Pathway: Difference between revisions
→Longevity-Relevant Biological Pathways
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!Notable Examples | !Notable Examples | ||
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|Insulin/IGF-1 Signaling (IIS) | |[[Insulin/IGF-1 Signaling (IIS) Pathway|Insulin/IGF-1 Signaling (IIS)]] | ||
|A pathway involved in the regulation of growth and metabolism in response to insulin and IGF-1. | |A pathway involved in the regulation of growth and metabolism in response to insulin and IGF-1. | ||
|Mutations and alterations in this pathway are linked to increased lifespan in various model organisms. | |Mutations and alterations in this pathway are linked to increased lifespan in various model organisms. | ||
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|Rapamycin | |Rapamycin | ||
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|Sirtuin Pathways | |[[Sirtuins|Sirtuin Pathways]] | ||
|Involves a family of proteins that regulate cellular health and are implicated in aging processes. | |Involves a family of proteins that regulate cellular health and are implicated in aging processes. | ||
|Sirtuins are associated with increased lifespan and improved health in response to caloric restriction. | |Sirtuins are associated with increased lifespan and improved health in response to caloric restriction. | ||