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Fasting-Mimicking Diet: Difference between revisions
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{{ | =Fasting-Mimicking Diet (FMD)= | ||
The '''Fasting-Mimicking Diet (FMD)''' is a nutritional protocol designed to achieve the benefits of fasting while still providing the body with nutrients. Developed by Dr. Valter Longo and his colleagues, FMD aims to mimic the physiological effects of traditional fasting, but in a way that is safer and more manageable for people to follow. The diet typically involves a reduced calorie intake, specific macronutrient ratios, and is followed for a period of five days each month. | |||
==Overview== | |||
FMD is based on the principle that certain dietary interventions can trigger some of the beneficial stress responses in the body that are activated by water fasting, such as autophagy (the process by which cells clean out damaged components), without the challenges and potential risks associated with complete food abstinence. The diet is low in calories, proteins, and sugars but high in unsaturated fats. | |||
==Research and Mechanisms== | |||
Research into FMD, led by Dr. Valter Longo and his team, has shown that it can lead to a reduction in biomarkers for aging, inflammation, and diseases in both animal models and humans. Studies have suggested that FMD can promote regenerative and rejuvenating changes in various biological systems, including the immune system, and may reduce risk factors associated with aging and age-related diseases. | |||
===Key Findings=== | |||
*Reduction in biomarkers for aging, inflammation, and diseases. | |||
*Improvement in markers of cardiovascular health. | |||
*Potential to promote autophagy and stem cell regeneration. | |||
==Potential Benefits== | |||
*'''Weight Loss:''' FMD can lead to a reduction in body weight and body fat. | |||
*'''Longevity:''' Animal studies suggest that FMD may extend lifespan. | |||
*'''Health Improvement:''' Potential benefits include improved metabolic health, reduced inflammation, and enhanced cognitive function. | |||
==How to Follow FMD== | |||
The diet typically involves consuming specially formulated meal kits that are low in calories, proteins, and sugars but high in unsaturated fats for five consecutive days, followed by a return to a normal diet for the rest of the month. It is recommended to undergo this diet under medical supervision, especially for individuals with pre-existing health conditions. | |||
==Safety and Considerations== | |||
While FMD is generally considered safe for healthy individuals, it is not suitable for everyone. Specific groups, such as pregnant women, individuals with a low body mass index (BMI), or those with certain medical conditions, should avoid this diet. Consulting with a healthcare provider before starting FMD is crucial. | |||
==References== | |||
*{{doi|10.1016/j.cell.2017.02.018}} - A study on the effects of FMD on markers of aging and disease. | |||
*{{pmid|26135345}} - Research on the impact of FMD on lifespan and healthspan in mice. | |||
*{{pmid|28202713}} - A study discussing the potential of FMD to promote human health and longevity. | |||
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