Resveratrol: Difference between revisions

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After consumption, 77-80% of resveratrol gets absorbed into the bloodstream through active transport via the intestinal epithelial cells. Once in the bloodstream, it associates with albumin and lipoproteins. Despite its efficient absorption, resveratrol possesses a short half-life of around 1.5 hours. This is attributed to its rapid absorption in the intestine and subsequent degradation in the liver. A significant amount of ingested resveratrol, approximately 49–61%, is eventually excreted through urine.
After consumption, 77-80% of resveratrol gets absorbed into the bloodstream through active transport via the intestinal epithelial cells. Once in the bloodstream, it associates with albumin and lipoproteins. Despite its efficient absorption, resveratrol possesses a short half-life of around 1.5 hours. This is attributed to its rapid absorption in the intestine and subsequent degradation in the liver. A significant amount of ingested resveratrol, approximately 49–61%, is eventually excreted through urine.


Several factors lead to differences in how individuals respond to RSV intake:
Several factors lead to differences in how individuals respond to RSV intake: <ref name=":0" />
* '''Gut Microbiota Composition:''' The unique blend of microorganisms in one's gut.
* '''Gut Microbiota Composition:''' The unique blend of microorganisms in one's gut.
* '''Genetic Differences:''' Variations in genes that affect metabolism enzymes (like UGTs and SULTs) and transporters.
* '''Genetic Differences:''' Variations in genes that affect metabolism enzymes (like UGTs and SULTs) and transporters.
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{| class="wikitable mw-collapsible mw-collapsed" style="width: 100%;"
{| class="wikitable mw-collapsible mw-collapsed" style="width: 100%;"
|+Reported resveratrol plasma concentration in humans after repeated doses of resveratrol (studies after 2010). <ref>https://www.mdpi.com/2072-6643/11/1/143</ref>
|+Reported resveratrol plasma concentration in humans after repeated doses of resveratrol (studies after 2010). <ref name=":0">https://www.mdpi.com/2072-6643/11/1/143</ref>
!Number of Participants, Characteristics, Study Type
!Number of Participants, Characteristics, Study Type
!Dose<br>(mg/day)
!Dose<br>(mg/day)