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Dose Conversion Between Animals and Human by Allometric Scaling: Difference between revisions
Dose Conversion Between Animals and Human by Allometric Scaling (view source)
Revision as of 11:57, 11 September 2023
, 11 September 2023→Human Equivalent Dose Calculation based on Body Surface Area
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The HED can be calculated by dividing the animal equivalent dose (AED) by the K<sub>m</sub> ratio: | The HED can be calculated by dividing the animal equivalent dose (AED) by the K<sub>m</sub> ratio. The unit of HED and AED is mg/kg. | ||
<math>HED = \frac{AED}{K_m\:ratio}</math> | |||
To get the final dose in mg, HED must be multiplied by the human weight: | |||
<math>Dose = HED * Weight_{human} = \frac{AED}{K_m\:ratio} * Weight_{human}</math> | |||
== References == | == References == | ||
<references /> | <references /> | ||