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Creatine: Difference between revisions
→Potential Longevity Benefits
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[[File:Creatine mice lifespan.gif|thumb|Survival rate of wild type mice after starting 1% creatine submission beginning in the age of 365 days]] | [[File:Creatine mice lifespan.gif|thumb|Survival rate of wild type mice after starting 1% creatine submission beginning in the age of 365 days]] | ||
In animal studies, creatine supplementation has been associated with a 9% increase in lifespan. Creatine-fed mice also demonstrated significantly better performance on neurobehavioral testing. While human trials are needed to confirm these findings, they suggest a potential benefit of creatine supplementation for longevity. | In animal studies, creatine supplementation has been associated with a 9% increase in lifespan. Creatine-fed mice also demonstrated significantly better performance on neurobehavioral testing. While human trials are needed to confirm these findings, they suggest a potential benefit of creatine supplementation for longevity. | ||
The average daily food intake for an adult female C57BL/6 mouse is approximately 2.5 to 5 grams per day and the typical weight is 20-25 grams. 1% of 3.75 g is 0.035 g creatine per day. 0.035 g / 22.5 is ~1555 mg/kg dose. That converts to ~126 mg/kg human equivalent dose or ~9500 mg/day for a 75 kg person. | |||
{{#pmid:17416441|pmid17416441}} | {{#pmid:17416441|pmid17416441}} | ||